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伴有皮肤损害的播散性隐球菌病:病例系列报告

Disseminated cryptococcosis with skin lesions: report of a case series.

作者信息

Hayashida Marina Zoéga, Seque Camila Arai, Pasin Victor Pavan, Enokihara Milvia Maria Simões E Silva, Porro Adriana Maria

机构信息

Department of Pathology, Escola Paulista de Medicina - Universidade Federal de São Paulo (EPM-UNIFESP) - São Paulo (SP), Brazil.

出版信息

An Bras Dermatol. 2017;92(5 Suppl 1):69-72. doi: 10.1590/abd1806-4841.20176343.

Abstract

Cryptococcosis is a common fungal infection in immunocompromised patients, caused by genus Cryptococcus, presenting with meningitis, pneumonia, and skin lesions. Cutaneous presentation can be varied, but specifically in solid organ transplant recipients (iatrogenically immunocompromised), cryptococcosis should always be considered in the differential diagnosis of cellulitis-like lesions, since the delay in diagnosis leads to worse prognosis and fatal outcome. We report four cases of cryptococcosis with cutaneous manifestation not only for its rarity, but also to emphasize the important role of the dermatologist in the diagnosis of this disease.

摘要

隐球菌病是免疫功能低下患者中常见的真菌感染,由隐球菌属引起,表现为脑膜炎、肺炎和皮肤病变。皮肤表现可能多种多样,但特别是在实体器官移植受者(医源性免疫功能低下)中,在鉴别诊断蜂窝织炎样病变时应始终考虑隐球菌病,因为诊断延迟会导致预后更差和致命后果。我们报告4例有皮肤表现的隐球菌病病例,不仅因其罕见,还为强调皮肤科医生在该病诊断中的重要作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b5a/5726682/9352e1e2b929/abd-92-05-s1-0069-g01.jpg

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