Muylaert Bianca Pinheiro Bousquet, Almada Roberta, Vasconcelos Rossana Cantanhede Farias de
Department of Dermatology of the Universidade de Santo Amaro (UNISA) - Santo Amaro (SP), Brazil.
Private practice - São Paulo (SP), Brazil.
An Bras Dermatol. 2017;92(5 Suppl 1):82-84. doi: 10.1590/abd1806-4841.20174994.
Granuloma annulare is a benign cutaneous inflammatory disease, whose lesions have spontaneous improvement in two years in 50% of cases, but there is recurrence in 40% of patients. Treatment may be topical, intralesional or systemic. The use of phototherapy with narrowband UVB is highlighted, whose mechanism of action in this disease is still unclear, probably related to the inhibition of T lymphocytes. Herein, a case of a disseminated granuloma annulare of difficult therapeutic management is described. It was treated with narrowband UVB phototherapy twice a week for six months, with good clinical improvement, being a good low-risk therapeutic option and that, in this case, provided quick and satisfactory response.
环状肉芽肿是一种良性皮肤炎症性疾病，其皮损在50%的病例中会在两年内自发改善，但40%的患者会复发。治疗方法可以是局部、皮损内或全身性的。窄谱中波紫外线光疗的应用受到关注，其在该疾病中的作用机制仍不清楚，可能与T淋巴细胞的抑制有关。在此，描述了一例治疗困难的播散性环状肉芽肿病例。该病例每周接受两次窄谱中波紫外线光疗，持续六个月，临床改善良好，是一种低风险的良好治疗选择，并且在该病例中提供了快速且令人满意的反应。
