免疫缺陷和免疫功能正常牙科患者牙菌斑微生物群的比较。
Comparison of the plaque microflora in immunodeficient and immunocompetent dental patients.
作者信息
Brown L R, Mackler B F, Levy B M, Wright T E, Handler S F, Moylan J S, Perkins D H, Keene H J
出版信息
J Dent Res. 1979 Dec;58(12):2344-52. doi: 10.1177/00220345790580120301.
The nature and extent of the immune dysfunctions in 20 immunodeficient patients, as well as the immunocompetence of 22 control subjects, were verified by cell-mediated responsiveness and immunoglobulin quantitations. Comparisons of the microbial composition of supragingival plaque between the two populations showed that a greater number of immunodeficient than control subjects harbored Candida sp. and Staphylococcus sp. Conversely, a lower number of immunodeficient than control subjects harbored Streptococcus mutans. Also, patients with immune dysfunctions had a lower dental caries experience than their immunocompetent counterparts.
通过细胞介导的反应性和免疫球蛋白定量分析，验证了20名免疫缺陷患者免疫功能障碍的性质和程度，以及22名对照受试者的免疫能力。对两组人群龈上菌斑微生物组成的比较表明，携带念珠菌属和葡萄球菌属的免疫缺陷患者数量多于对照受试者。相反，携带变形链球菌的免疫缺陷患者数量少于对照受试者。此外，免疫功能障碍患者的龋齿经历少于免疫功能正常的同龄人。
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