Zhou Zhi-Qiang, Fan Long-Chang, Zhao Xu, Xia Wei, Luo Ai-Lin, Tian Yu-Ke, Wang Xue-Ren
Department of Anesthesiology, Huazhong University of Science and Technology, Wuhan, 430030, China.
Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
J Huazhong Univ Sci Technolog Med Sci. 2017 Dec;37(6):861-863. doi: 10.1007/s11596-017-1818-5. Epub 2017 Dec 21.
Acute kidney injury (AKI) is a common complication following orthotopic liver transplantation (OLT) and is associated with increased morbidity and mortality. The aim of the current study was to determine the risk factors for AKI in patients undergoing OLT. A total of 103 patients who received OLT between January 2015 and May 2016 in Tongji Hospital, China, were retrospectively analyzed. Their demographic characteristics and perioperative parameters were collected, and AKI was diagnosed using 2012 Kidney Disease: Improving Global Outcomes (KDIGO) staging criteria. It was found that the incidence of AKI was 40.8% in this cohort and AKI was significantly associated with body mass index, urine volume, operation duration (especially > 480 min), and the postoperative use of vasopressors. It was concluded that relative low urine output, long operation duration, and the postoperative use of vasopressors are risk factors for AKI following OLT.
急性肾损伤（AKI）是原位肝移植（OLT）术后常见的并发症，与发病率和死亡率增加相关。本研究的目的是确定接受OLT患者发生AKI的危险因素。对2015年1月至2016年5月在中国同济医院接受OLT的103例患者进行回顾性分析。收集他们的人口统计学特征和围手术期参数，并使用2012年改善全球肾脏病预后组织（KDIGO）分期标准诊断AKI。结果发现，该队列中AKI的发生率为40.8%，AKI与体重指数、尿量、手术时间（尤其是>480分钟）以及术后使用血管升压药显著相关。得出的结论是，相对低尿量、手术时间长以及术后使用血管升压药是OLT术后发生AKI的危险因素。
