Jevning R, Fernando G, Wilson A F
Department of Medicine, University of California, Irvine, Orange 92668.
J Biomed Eng. 1989 Jan;11(1):53-6. doi: 10.1016/0141-5425(89)90166-0.
Significant correlation was observed, in normal resting individuals, of interregional variation of classical amplitude-dependent electrical impedance indices of cerebral blood flow (CBF) with three quantitative rheographic measures of cerebral blood flow which have been themselves radioisotopically validated. Since these amplitude-related CBF indices are derived from the Nyboer model relating blood volume changes to change of impedance, the data support the correctness and applicability of this model to the head. Interrelationship among the CBF parameters obtained with the use of this technique was found to be markedly affected by differing electrode placements; it was not apparently affected by extracranial circulation. It is concluded that under proper recording conditions, several assumptions underlying rheoencephalography are consistent and that it may be a useful tool for the study of relative regional cerebral blood flow in normal individuals.
在正常静息个体中，观察到脑血流量（CBF）的经典幅度依赖性电阻抗指数的区域间变化与三种脑血流量的定量血流图测量值之间存在显著相关性，而这三种测量值本身已通过放射性同位素验证。由于这些与幅度相关的CBF指数源自将血容量变化与阻抗变化相关联的尼伯尔模型，因此数据支持该模型对头的正确性和适用性。发现使用该技术获得的CBF参数之间的相互关系受到不同电极放置的显著影响；它显然不受颅外循环的影响。得出的结论是，在适当的记录条件下，脑电阻抗图的几个基本假设是一致的，并且它可能是研究正常个体相对局部脑血流量的有用工具。
