Translational Medical Device Lab, National University of Ireland Galway, Galway City, Ireland. Department of Electrical and Electronic Engineering, College of Engineering and Informatics, National University of Ireland Galway, Galway City, Ireland.
Physiol Meas. 2018 Mar 15;39(3):034001. doi: 10.1088/1361-6579/aaa3c0.
To design and fabricate an anatomically and conductively accurate phantom for electrical impedance studies of non-invasive bladder volume monitoring.
A modular pelvic phantom was designed and fabricated, consisting of a mechanically and conductively stable boundary wall, a background medium, and bladder phantoms. The wall and bladders are made of conductive polyurethane. The background material is an ultrasound gel-based mixture, with conductivity matched to a weighted average of the pelvic cavity organs, bone, muscle and fat. The phantom boundary is developed using a computer tomography model of a male human pelvis. The bladder phantoms were designed to correlate with human bladder dimensions. Electrical impedance measurements of the phantom were recorded, and images produced using six different bladder phantoms and a realistic finite element model.
Five different bladder volumes were successfully imaged using an empty bladder as a reference. The average conductivity index from the reconstructed images showed a strong positive correlation with the bladder phantom volumes.
A conductively and anatomically accurate pelvic phantom was developed for non-invasive bladder volume monitoring using electrical impedance measurements. Several bladders were designed to correlate with actual human bladder volumes, allowing for accurate volume estimation. The conductivity of the phantom is accurate over 50-250 kHz. This phantom can allow changeable electrode location, contact and size; multi-layer electrodes configurations; increased complexity by addition of other organ or bone phantoms; and electrode movement and deformation. Overall, the pelvic phantom enables greater scope for experimentation and system refinement as a precursor to in-man clinical studies.
设计并制作一种解剖学和电导率准确的体模,用于非侵入式膀胱容量监测的电阻抗研究。
设计并制作了一种模块化的骨盆体模,由机械和电导率稳定的边界壁、背景介质和膀胱体模组成。壁和膀胱由导电聚氨酯制成。背景材料是一种基于超声凝胶的混合物,其电导率与骨盆器官、骨骼、肌肉和脂肪的加权平均值相匹配。体模边界是使用男性人体骨盆的计算机断层扫描模型开发的。膀胱体模的设计与人体膀胱尺寸相关。记录了体模的电阻抗测量值,并使用六个不同的膀胱体模和一个现实的有限元模型生成了图像。
使用空膀胱作为参考,成功地对五个不同的膀胱容量进行了成像。重建图像的平均电导率指数与膀胱体模容量呈强烈正相关。
开发了一种解剖学和电导率准确的骨盆体模,用于使用电阻抗测量的非侵入式膀胱容量监测。设计了几个膀胱来与实际的人体膀胱容量相关,以实现准确的容量估计。体模的电导率在 50-250 kHz 范围内是准确的。该体模允许改变电极位置、接触和大小;多层电极配置;通过添加其他器官或骨骼体模增加复杂性;以及电极的移动和变形。总体而言,该骨盆体模为实验和系统改进提供了更大的空间,作为人体临床研究的前奏。