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将菖蒲用作预防和治疗心血管疾病的有前景的生物活性化合物来源是否安全?

Is it safe to use Acorus calamus as a source of promising bioactive compounds in prevention and treatment of cardiovascular diseases?

作者信息

Olas Beata, Bryś Magdalena

机构信息

Department of General Biochemistry, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland.

Department of Cytobiochemistry, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland.

出版信息

Chem Biol Interact. 2018 Feb 1;281:32-36. doi: 10.1016/j.cbi.2017.12.026. Epub 2017 Dec 19.

DOI:10.1016/j.cbi.2017.12.026
PMID:29273563
Abstract

Acorus calamus has a rich history in natural medicine, and offers many health benefits. The plant has anti-inflammatory, antimicrobial, diuretic, antiurolithiatic and other properties. Moreover, various parts, especially the rhizome and roots, are sources of a range of bioactive phenolic compounds with beneficial effects on the cardiovascular system. This review article summarizes the current knowledge of the chemical composition of different parts of A. calamus and their roles in the prevention and treatment of cardiovascular diseases. However, as no human studies have been performed, the review only includes in vitro and animal studies. The paper also briefly reviews the toxicity of A. calamus and its products for human health, especially regarding the cardiovascular system.

摘要

菖蒲在天然药物领域有着悠久的历史,并具有诸多健康益处。该植物具有抗炎、抗菌、利尿、抗尿路结石等特性。此外,菖蒲的各个部位,尤其是根茎和根部,富含一系列对心血管系统有益的生物活性酚类化合物。这篇综述文章总结了菖蒲不同部位的化学成分及其在心血管疾病预防和治疗中的作用的现有知识。然而,由于尚未进行人体研究,该综述仅纳入了体外研究和动物研究。本文还简要回顾了菖蒲及其产品对人体健康的毒性,特别是对心血管系统的毒性。

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