Kempster P A, Lees A J, Crichton P, Frankel J P, Shorvon P
Department of Neurology, Middlesex Hospital, London, United Kingdom.
Mov Disord. 1989;4(1):47-52. doi: 10.1002/mds.870040108.
Two L-dopa-treated patients with Parkinson's disease who developed distressing belching during "off" periods are reported. In each case, contrast cine radiography revealed disturbed oesophageal motility which disappeared after injection of the dopamine receptor agonist apomorphine. It is suggested that central dopaminergic abnormalities may be important in the aetiology of "off period belching."
报告了两名接受左旋多巴治疗的帕金森病患者，他们在“关”期出现令人苦恼的嗳气。在每个病例中，对比电影造影显示食管动力紊乱，在注射多巴胺受体激动剂阿扑吗啡后消失。提示中枢多巴胺能异常可能在“关期嗳气”的病因中起重要作用。
