Flores-Ruiz R, Castellanos-Cosano L, Serrera-Figallo M-A, Gutiérrez-Corrales A, Castillo-Oyague R, Gutiérrez-Perez J-L, Torres-Lagares D
Departament of Stomatology School of Dentistry, C/ Avicena s/n, 41009 Seville, Spain,
Med Oral Patol Oral Cir Bucal. 2018 Jan 1;23(1):e86-e91. doi: 10.4317/medoral.21839.
Head and neck cancer are one of the most common neoplasm pathologies in humans. The aim of this study was to analyze the type, characteristics, treatment and evolution of oral neoplasm or precancerous lesion in a sample of Andalusian population (Spain) derived from the Oncology Rehabilitation Hospital Unit during a period of 20 years.
A retrospective descriptive study was carried out during the years 1991 and 2011 analyzing the type, characteristics, treatment and follow-up of oral neoplasm in the Oral and Maxillofacial Surgery Unit of the Universitary Hospital Virgen del Rocio. The inclusion criteria were patients whose underlying pathology was any type of benign or malignant neoplasm or presence of precancerous lesion that, after treatment, had been referred to the Prosthetic Rehabilitation Unit.
Of the initial analyzed sample of 60 patients, only 45 patients met the inclusion criteria. Of the final sample analyzed, 31 subjects were men (68.9%) and 14 women (31.1%) (p = 0.0169). The mean age of the sample was 57 years ± 13.83, been more frequently in older people with more than 50 years (73.3%) (p = 0.0169). The most common type of neoplasm was epidermoid carcinoma (64.4%). The site most frequently found in squamous cell carcinoma was the floor of the mouth (31%). The most frequent treatment modality was surgery with postoperative radiotherapy (42.2%). All patients had a minimum follow-up of 5 years, and a recurrence in this period was identified in 11.1% of the sample. Multivariate logistic regression showed a statistically significant association for the variables age (p = 0.0063) and smoking (p = 0.0434).
Epidermoid carcinoma is the most frequent tumor in the oral cavity, where increase age and smoking are confirmed as associated risk factors.
头颈癌是人类最常见的肿瘤病理类型之一。本研究的目的是分析来自西班牙安达卢西亚地区肿瘤康复医院的样本中，20年间口腔肿瘤或癌前病变的类型、特征、治疗及转归情况。
1991年至2011年进行了一项回顾性描述性研究，分析了罗西奥圣母大学医院口腔颌面外科单元口腔肿瘤的类型、特征、治疗及随访情况。纳入标准为基础病理为任何类型的良性或恶性肿瘤或存在癌前病变，且治疗后转诊至修复康复单元的患者。
在最初分析的60例患者样本中，只有45例符合纳入标准。在最终分析的样本中，31例为男性（68.9%），14例为女性（31.1%）（p = 0.0169）。样本的平均年龄为57岁±13.83岁，50岁以上的老年人更为常见（73.3%）（p = 0.0169）。最常见的肿瘤类型是表皮样癌（64.4%）。鳞状细胞癌最常发生的部位是口底（31%）。最常见的治疗方式是手术加术后放疗（42.2%）。所有患者的最短随访时间为5年，在此期间样本中有11.1%出现复发。多因素逻辑回归显示年龄（p = 0.0063）和吸烟（p = 0.0434）这两个变量具有统计学意义的关联。
表皮样癌是口腔中最常见的肿瘤，年龄增长和吸烟被确认为相关危险因素。
