Agence de la biomédecine, direction prélèvement greffe organes-tissus, 1, avenue du Stade-de-France, 93212 Saint-Denis-La-Plaine cedex, France.
Département de cardiologie, hôpital Pitié-Salpêtrière, Assistance publique-Hôpitaux de Paris, 75013 Paris, France.
Arch Cardiovasc Dis. 2018 Feb;111(2):126-139. doi: 10.1016/j.acvd.2017.12.001. Epub 2017 Dec 23.
Assessment of potential donors is an essential part of heart transplantation. Despite the shortage of donor hearts, donor heart procurement from brain-dead organ donors remains low in France, which may be explained by the increasing proportion of high-risk donors, as well as the mismatch between donor assessment and the transplant team's expectations. Improving donor and donor heart assessment is essential to improve the low utilization rate of available donor hearts without increasing post-transplant recipient mortality. This document provides information to practitioners involved in brain-dead donor management, evaluation and selection, concerning the place of medical history, electrocardiography, cardiac imaging, biomarkers and haemodynamic and arrhythmia assessment in the characterization of potential heart donors.
评估潜在供体是心脏移植的重要组成部分。尽管供心短缺，但法国脑死亡器官供体获取量仍然较低，这可能是由于高危供体比例增加，以及供体评估与移植团队期望之间不匹配所致。改善供体和供心评估对于提高可用供心的低利用率而不增加移植后受体死亡率至关重要。本文为参与脑死亡供体管理、评估和选择的临床医生提供信息，涉及病史、心电图、心脏影像学、生物标志物以及血流动力学和心律失常评估在潜在心脏供体特征描述中的作用。
