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手术治疗输卵管妊娠性绒毛膜癌后盆腔复发的减瘤手术——病例报告及文献综述

Debulking Surgery for Pelvic Recurrence After Surgically-treated Tubal Gestational Choriocarcinoma - A Case Report and Literature Review.

作者信息

Bacalbasa Nicolae, Balescu Irina, Brasoveanu Vladislav, Anca Alexandru Florin

机构信息

"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.

"Ponderas Academic Hospital", Bucharest, Romania

出版信息

Anticancer Res. 2018 Jan;38(1):423-426. doi: 10.21873/anticanres.12239.

Abstract

Gestational choriocarcinomas are very rare malignancies, with only few cases being reported so far. Moreover, the presence of pelvic recurrences after surgically-treated gestational choriocarcinomas is even scarcer situations. We present the case of a 19-year-old patient who was initially submitted to surgery with preoperative diagnosis of ectopic pregnancy. At that moment a left salpingectomy was performed, and the histopathological studies revealed the presence of a left tubal gestational choriocarcinoma. The patient was submitted to adjuvant chemotherapy with methotrexate and dactinomycin. However, six months later she was diagnosed with a pelvic recurrence so she was resubmitted to surgery, debulking to no residual disease being successfully performed. The histopathological studies confirmed the presence of a recurrent tumor with gestational choriocarcinoma structure.

摘要

妊娠性绒毛膜癌是非常罕见的恶性肿瘤,迄今为止仅有少数病例报道。此外,手术治疗后的妊娠性绒毛膜癌出现盆腔复发的情况更为罕见。我们报告一例19岁患者,最初因术前诊断为异位妊娠而接受手术。当时进行了左侧输卵管切除术,组织病理学研究显示存在左侧输卵管妊娠性绒毛膜癌。该患者接受了甲氨蝶呤和放线菌素D的辅助化疗。然而,六个月后她被诊断为盆腔复发,因此再次接受手术,成功地进行了肿瘤减灭术,无残留病灶。组织病理学研究证实存在具有妊娠性绒毛膜癌结构的复发性肿瘤。

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