牙周治疗对糖尿病结局影响的潜在作用的证据更新。

An update of the evidence on the potential impact of periodontal therapy on diabetes outcomes.

机构信息

Department of Periodontology, School of Dentistry, National and Kapodistrian University of Athens, Athens, Greece.

出版信息

J Clin Periodontol. 2018 Feb;45(2):188-195. doi: 10.1111/jcpe.12836. Epub 2017 Dec 26.

DOI:10.1111/jcpe.12836

PMID:29277978

Abstract

AIM

To provide an update of the systematic review by Engebretson and Kocher J Clin Periodontol. 2013 Apr;40 Suppl 14:S153 on the effect of periodontal therapy on glycaemic control of people with diabetes.

METHODS

PubMed Literature search restricted to meta-analyses published from 2013 to the present was conducted. The search resulted in seven meta-analyses of RCTs.

RESULTS

Reduction in HbA1c at 3-4 months was reported in all reviews for the treatment group ranging from -0.27% (95% CI: -0.46, -0.07, p = .007) to -1.03% (95% CI: 0.36, -1.70, p = 0.003). At 6 months post-treatment, an HbA1c reduction ranging from -0.02 (95% CI: -0.20, -0.16, p = .84) to -1.18% (95% CI: 0.72%, 1.64%, p < 0.001) was reported.

CLINICAL RELEVANCE

The magnitude of the reduction in HbA1c, which is found to be associated with non-surgical periodontal treatment in patients with diabetes, seems to have clinically significant effects on systemic health, and thus should have a place in the treatment of diabetic patients.

CONCLUSIONS

Periodontal treatment (SRP) results in a statistically significant reduction in HbA1C levels at 3 months, with a lower reduction at 6 months.

摘要

目的

对 Engebretson 和 Kocher 发表于 2013 年 4 月《临床牙周病学杂志》40 增刊 14 期的综述进行更新，该综述评估了牙周治疗对糖尿病患者血糖控制的影响。

方法

对 2013 年至今发表的荟萃分析进行了 PubMed 文献检索，共检索到 7 篇 RCT 的荟萃分析。

结果

所有综述均报道了治疗组在 3-4 个月时 HbA1c 的降低，范围为-0.27%（95% CI：-0.46，-0.07，p = 0.007）至-1.03%（95% CI：0.36，-1.70，p = 0.003）。在治疗后 6 个月时，HbA1c 的降低范围为-0.02（95% CI：-0.20，-0.16，p = 0.84）至-1.18%（95% CI：0.72%，1.64%，p < 0.001）。