Department of Radiology, Jinshan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Department of Radiology, Jinshan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Eur J Radiol. 2018 Jan;98:136-142. doi: 10.1016/j.ejrad.2017.11.014. Epub 2017 Nov 22.
To identify the MRI features of borderline epithelial ovarian tumors (BEOTs) and to differentiate BEOTs from malignant epithelial ovarian tumors (MEOTs).
The clinical and MRI data of 89 patients with a BEOT and 109 patients with a MEOT proven by surgery and histopathology were retrospectively reviewed. MRI features, including bilaterality, size, shape, margin, cystic-solid interface, configuration, papillae or nodules, signal intensity, enhancement, presence of an ipsilateral ovary, peritoneal implants and ascites were analyzed and compared. Based on the odds ratio (OR) values, the significant risk features for BEOTs were scored as 3 (OR≈∞), 2 (5≤OR<∞) or 1 (OR<5).
There were 89 BEOT patients with 113 tumors [mean size of (13±6.7)cm], with bilateral ovary involvement in 24 cases. There were 109 MEOT patients with 142 tumors [(9.3±4.2)cm] with bilateral ovary involvement in 33 cases. There were eight significant risk factors for BEOTs, including round or oval shape (OR=2.714), well-defined margins (OR=3.318), clear cystic-solid interfaces (OR=5.593), purely cystic (OR=15.206), predominantly cystic with papillae or nodules (OR=2.579), exophytic papillae or nodules (OR=5.351), branching papilla (OR≈∞) and the presence of an ipsilateral ovary (OR≈∞). Based on the scoring of the eight risk factors, a cut-off score of 3.5 yielded a differential sensitivity, specificity, and accuracy of 82%, 85% and 84%, respectively.
In contrast to MEOTs, BEOTs frequently had the following features on MRI: round or oval, with well-defined margins and clear cystic-solid interfaces, purely cystic or predominantly cystic with papillae or nodules, branching or exophytic papillae, with the presence of an ipsilateral ovary. MRI can reveal the distinct morphological features of BEOTs and MEOTs and facilitate their discrimination.
识别交界性卵巢上皮性肿瘤（BEOT）的 MRI 特征，并将其与恶性上皮性卵巢肿瘤（MEOT）区分开来。
回顾性分析了 89 例经手术和组织病理学证实的 BEOT 患者和 109 例 MEOT 患者的临床和 MRI 资料。分析比较了 MRI 特征，包括双侧性、大小、形状、边缘、囊实性界面、形态、乳头或结节、信号强度、强化、同侧卵巢、腹膜种植和腹水的存在。根据比值比（OR）值，将 BEOT 的显著风险特征评分 3 分（OR≈∞）、2 分（5≤OR<∞）或 1 分（OR<5）。
89 例 BEOT 患者共有 113 个肿瘤[（13±6.7）cm]，24 例双侧卵巢受累。109 例 MEOT 患者共有 142 个肿瘤[（9.3±4.2）cm]，33 例双侧卵巢受累。BEOT 有 8 个显著的风险因素，包括圆形或椭圆形（OR=2.714）、边界清楚（OR=3.318）、清晰的囊实性界面（OR=5.593）、单纯性囊性（OR=15.206）、以囊性为主伴乳头或结节（OR=2.579）、外生性乳头或结节（OR=5.351）、分支状乳头（OR≈∞）和同侧卵巢存在（OR≈∞）。根据 8 个风险因素的评分，截断值为 3.5 时，鉴别诊断的敏感性、特异性和准确性分别为 82%、85%和 84%。
与 MEOT 相比，BEOT 在 MRI 上常有以下特征：圆形或椭圆形，边界清楚，囊实性界面清晰，单纯性囊性或以囊性为主伴乳头或结节，分支状或外生性乳头，同侧卵巢存在。MRI 可以揭示 BEOT 和 MEOT 的独特形态学特征，有助于两者的鉴别诊断。
