Dimitrova Alexandra
Department of Neurology, Oregon Health & Science University, Portland, OR.
Med Acupunct. 2017 Dec 1;29(6):352-365. doi: 10.1089/acu.2017.1242.
Peripheral neuropathy (PN) is defined as damage to the peripheral nervous system caused by a primary lesion or dysfunction. Multiple recent trials have suggested that acupuncture is beneficial for treating neuropathic pain. One challenge in acupuncture research is the lack of standardization of point selection, number of needles used, needle-retention time, needling depth, amount of needle manipulation, and use of moxibustion and electroacupuncture (EA). This article presents a standardized acupuncture protocol for the treatment of PN that incorporates structural acupuncture principles based on proximity to peripheral nerves and on traditional approaches to the treatment of neuropathic pain. Ten consecutive patients diagnosed with large- or small-fiber neuropathy of various etiologies were treated with a standardized protocol, based on anatomical correlations of peripheral nerves and acupuncture points. Manual acupuncture was applied to left LR 4, LU 5; bilateral LI 11, KI 27, ST 36, GB 34, SP 6, SP 9, LI 4, TE 5, and (except for the space between the first and second digits of the toes; LR 3 was used for that space). EA was applied to bilateral KI 3-1 and bilateral ST 41-LR 3. Patients underwent at least six acupuncture sessions, although the total number of sessions varied. Outcomes were measured using a visual analogue scale (VAS) and clinical signs and symptoms. All 10 patients indicated improvement on the VAS and in clinical presentation. This standardized protocol appears to be effective for the treatment of neuropathy of various causes, including large- and small-fiber involvement. Further studies with larger sample sizes and randomized comparisons against sham acupuncture and other acupuncture regimens will be helpful to determine if this protocol could be established as a guideline for approaching peripheral neuropathy.
周围神经病变(PN)被定义为由原发性病变或功能障碍引起的周围神经系统损伤。最近的多项试验表明,针灸对治疗神经性疼痛有益。针灸研究中的一个挑战是在穴位选择、针刺数量、留针时间、针刺深度、手法操作量以及艾灸和电针(EA)的使用方面缺乏标准化。本文提出了一种用于治疗PN的标准化针灸方案,该方案结合了基于与周围神经的接近程度以及神经性疼痛传统治疗方法的结构针灸原则。根据周围神经与穴位的解剖学相关性,采用标准化方案对连续10例诊断为各种病因的大纤维或小纤维神经病变患者进行治疗。对左侧足厥阴肝经4穴、手太阴肺经5穴;双侧手阳明大肠经11穴、足少阴肾经27穴、足阳明胃经36穴、足少阳胆经34穴、足太阴脾经6穴、足太阴脾经9穴、手阳明大肠经4穴、手少阳三焦经5穴进行手动针刺,(除脚趾第一和第二趾之间的部位;该部位使用足厥阴肝经3穴)。对双侧肾经3 - 1穴和双侧胃经41 - 足厥阴肝经3穴进行电针治疗。患者至少接受6次针灸治疗,尽管治疗总次数有所不同。使用视觉模拟量表(VAS)以及临床体征和症状来衡量治疗效果。所有10例患者在VAS评分和临床表现方面均显示有所改善。这种标准化方案似乎对治疗各种原因引起的神经病变有效,包括大纤维和小纤维受累情况。进一步开展更大样本量的研究,并与假针刺和其他针灸方案进行随机对照比较,将有助于确定该方案是否可以确立为治疗周围神经病变的指南。