Sato Hiroki, Tsukahara Kiyoaki, Motohashi Ray, Wakiya Midori, Serizawa Hiromi, Kurata Atsushi
Department of Otorhinolaryngology, Head and Neck Surgery, Tokyo Medical University, Tokyo, Japan.
Department of Pathology, Tokyo Medical University Hachioji Medical Center, Tokyo, Japan.
Case Rep Otolaryngol. 2017;2017:4592783. doi: 10.1155/2017/4592783. Epub 2017 Nov 27.
Thyroid carcinoma complicated by hemiagenesis is very rare, and previous reports have not described this cancer on the side of the absent lobe.
We report the case of a 64-year-old woman in whom left thyroid hemiagenesis was discovered incidentally during investigations of abnormal sensation during swallowing. A tumorous 1.4 cm lesion was also found on the side of the absent lobe, left of the isthmus. Fine-needle aspiration biopsy revealed class V papillary carcinoma, but no lymph node metastases. Total thyroidectomy was performed for stage cT1bN0M0 carcinoma. Histopathology revealed normal thyroid tissues in the right lobe and isthmus, while the left lobe was absent. The mostly papillary carcinoma was adjacent to the truncated thyroid tissue, with a portion histologically consistent with poorly differentiated carcinoma.
All previously reported cases of thyroid cancer complicated by hemiagenesis have represented carcinoma occurring within the present lobe. This case is extremely rare.
甲状腺癌合并半侧甲状腺缺如极为罕见，既往报道未描述缺如叶侧的此类癌症。
我们报告一例64岁女性病例，该患者在吞咽异常感觉检查中偶然发现左侧甲状腺半侧缺如。在峡部左侧缺如叶侧还发现一个1.4 cm的肿瘤性病变。细针穿刺活检显示为V级乳头状癌，但无淋巴结转移。对cT1bN0M0期癌行全甲状腺切除术。组织病理学检查显示右叶和峡部甲状腺组织正常，而左叶缺如。大部分为乳头状癌，与截断的甲状腺组织相邻，部分组织学表现符合低分化癌。
既往报道的所有甲状腺癌合并半侧甲状腺缺如病例均为现存叶内发生的癌。本病例极为罕见。
