甲状腺半侧发育不全患者缺如叶侧的甲状腺癌

Thyroid Carcinoma on the Side of the Absent Lobe in a Patient with Thyroid Hemiagenesis.

作者信息

Sato Hiroki, Tsukahara Kiyoaki, Motohashi Ray, Wakiya Midori, Serizawa Hiromi, Kurata Atsushi

机构信息

Department of Otorhinolaryngology, Head and Neck Surgery, Tokyo Medical University, Tokyo, Japan.

Department of Pathology, Tokyo Medical University Hachioji Medical Center, Tokyo, Japan.

出版信息

Case Rep Otolaryngol. 2017;2017:4592783. doi: 10.1155/2017/4592783. Epub 2017 Nov 27.

BACKGROUND

Thyroid carcinoma complicated by hemiagenesis is very rare, and previous reports have not described this cancer on the side of the absent lobe.

METHODS AND RESULTS

We report the case of a 64-year-old woman in whom left thyroid hemiagenesis was discovered incidentally during investigations of abnormal sensation during swallowing. A tumorous 1.4 cm lesion was also found on the side of the absent lobe, left of the isthmus. Fine-needle aspiration biopsy revealed class V papillary carcinoma, but no lymph node metastases. Total thyroidectomy was performed for stage cT1bN0M0 carcinoma. Histopathology revealed normal thyroid tissues in the right lobe and isthmus, while the left lobe was absent. The mostly papillary carcinoma was adjacent to the truncated thyroid tissue, with a portion histologically consistent with poorly differentiated carcinoma.

CONCLUSIONS

All previously reported cases of thyroid cancer complicated by hemiagenesis have represented carcinoma occurring within the present lobe. This case is extremely rare.

背景

甲状腺癌合并半侧甲状腺缺如极为罕见，既往报道未描述缺如叶侧的此类癌症。

方法与结果

我们报告一例64岁女性病例，该患者在吞咽异常感觉检查中偶然发现左侧甲状腺半侧缺如。在峡部左侧缺如叶侧还发现一个1.4 cm的肿瘤性病变。细针穿刺活检显示为V级乳头状癌，但无淋巴结转移。对cT1bN0M0期癌行全甲状腺切除术。组织病理学检查显示右叶和峡部甲状腺组织正常，而左叶缺如。大部分为乳头状癌，与截断的甲状腺组织相邻，部分组织学表现符合低分化癌。