Needle David B, Iglikova Olga, Miller Andrew D
New Hampshire Veterinary Diagnostic Laboratory, College of Life Sciences and Agriculture, University of New Hampshire, Durham, NH (Needle).
Revere Pet Clinic, Revere, MA (Iglikova).
J Vet Diagn Invest. 2018 Mar;30(2):315-318. doi: 10.1177/1040638717752424. Epub 2017 Dec 28.
A 7-y-old Black Russian Terrier dog was evaluated for chronic lameness of the right forelimb and concurrent weight loss. Clinical examination revealed a pigmented mass arising from digit 4 of the right forelimb; the digit was amputated and submitted for histologic evaluation. Histologically, the neoplasm was composed of ill-defined streams, sheets, and clusters of melanocytes admixed with a distinct population of malignant epithelial cells forming glands and nests. The diagnosis was a biphasic malignant melanoma adenocarcinoma, a rarely reported neoplasm in human medicine that has not been described in veterinary medicine, to our knowledge.
一只7岁的黑俄罗斯梗犬因右前肢慢性跛行和体重减轻而接受评估。临床检查发现右前肢第4趾出现一个色素沉着肿块；该趾被截肢并送去进行组织学评估。组织学上，肿瘤由界限不清的条索、片层和黑素细胞簇组成，混有一群独特的形成腺体和巢状结构的恶性上皮细胞。诊断为双相性恶性黑色素瘤腺癌，据我们所知，这是一种在人类医学中很少报道、在兽医学中尚未描述过的肿瘤。
