2只犬的恶性直肠黑色素瘤
Malignant rectal melanoma in 2 dogs.
作者信息
Clarke Lorelei L, Rissi Daniel R
机构信息
Athens Veterinary Diagnostic Laboratory and Department of Pathology, University of Georgia College of Veterinary Medicine, Athens, Georgia, USA.
出版信息
Can Vet J. 2018 Feb;59(2):152-154.
Abstract
Two rare cases of malignant rectal melanoma in dogs are described. Tumors were locally invasive and composed of spindle cells arranged in interweaving bundles, sheets, and nests within preexisting fibrovascular stroma. Mitotic count was high. The diagnosis was achieved based on histopathology and immunohistochemistry for PNL2 and melan-A.
摘要
本文描述了两例犬恶性直肠黑色素瘤的罕见病例。肿瘤具有局部侵袭性，由梭形细胞组成，这些细胞在先前存在的纤维血管基质中呈交织束状、片状和巢状排列。有丝分裂计数较高。诊断基于组织病理学以及针对PNL2和黑色素A的免疫组织化学检查。
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