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[γ射线照射后长时间间隔下大鼠胸腺细胞核与染色质中的胆固醇和脂肪酸]

[Cholesterol and fatty acids of the nuclei and chromatin of the rat thymus at long intervals following gamma irradiation].

作者信息

Kulagina T P

出版信息

Radiobiologiia. 1990 May-Jun;30(3):317-20.

PMID:2371388
Abstract

The content of a total fraction of free fatty acids (FFA) and cholesterol in the chromatin, nuclei and homogenate of rat thymus were studied during three months following fractionated gamma-irradiation (2 Gy X 3 at a week interval). The FFA content in the homogenate, nuclei and chromatin of rat thymus drastically increased 60 min after the last exposure. In a month, the FFA content of nuclei and chromatin dropped to control levels, whereas that of the homogenate remained high throughout the entire period of observation and sharply increased by the third month. No changes were revealed in the cholesterol content.

摘要

在分次γ射线照射(2 Gy×3,间隔1周)后的三个月内,研究了大鼠胸腺染色质、细胞核和匀浆中游离脂肪酸(FFA)和胆固醇的总含量。最后一次照射60分钟后,大鼠胸腺匀浆、细胞核和染色质中的FFA含量急剧增加。一个月后,细胞核和染色质中的FFA含量降至对照水平,而匀浆中的FFA含量在整个观察期内一直保持较高水平,并在第三个月急剧增加。胆固醇含量未发现变化。

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