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韩国外科医生对保乳手术后切缘状态的实践模式与认知

The Practice Patterns and Perceptions of Korean Surgeons Regarding Margin Status after Breast-Conserving Surgery.

作者信息

Yoo Tae-Kyung, Kim Sung-Won, Kang Eunyoung, Ahn Sung Gwe, Hwang Ki-Tae, Kim Seung-Ki, Woo Sang Uk, Shin Hyuk Jai, Song Young-Jin, Jung Eun-Jung, Chang Myung-Chul, Lee Ilkyun, Park Woo-Chan

机构信息

Department of Surgery, Seoul St. Mary's Hospital, The Catholic University of Korea College of Medicine, Seoul, Korea.

Department of Surgery, Daerim St. Mary's Hospital, Seoul, Korea.

出版信息

J Breast Cancer. 2017 Dec;20(4):400-403. doi: 10.4048/jbc.2017.20.4.400. Epub 2017 Dec 19.

DOI:10.4048/jbc.2017.20.4.400
PMID:29285046
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5744001/
Abstract

Two consecutive surveys for breast surgeons in Korea were conducted to comprehend the practice patterns and perceptions on margin status after breast-conserving surgery. The surveys were conducted online in 2014 (initial) and 2016 (follow-up). A total of 126 and 88 responses were obtained in the initial and follow-up survey, respectively. More than 80% of the respondents replied to routinely apply frozen section biopsy for intraoperative margin assessment in both surveys. Re-excision recommendations of the margin for invasive cancer significantly changed from a close margin to a positive margin over time (=0.033). Most of the respondents (73.8%) defined a negative margin as "no ink on tumor" in invasive cancer, whereas more diverse responses were observed in ductal carcinoma cases. The influence of guideline establishment for negative margins has been identified. A high uptake rate of intraoperative frozen section biopsy was noted and routine use needs reconsideration.

摘要

为了解保乳手术后切缘状态的实践模式和认知情况,韩国对乳腺外科医生进行了两次连续调查。调查于2014年(首次)和2016年(随访)通过网络进行。首次调查和随访调查分别获得了126份和88份回复。在两次调查中,超过80%的受访者表示常规应用冰冻切片活检进行术中切缘评估。随着时间推移,浸润性癌切缘再次切除的建议从近切缘显著变为阳性切缘(P=0.033)。大多数受访者(73.8%)将浸润性癌的阴性切缘定义为“肿瘤上无墨水”,而在导管癌病例中观察到更多样化的回答。已确定了阴性切缘指南制定的影响。术中冰冻切片活检的采用率较高,常规使用需要重新考虑。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85fc/5744001/3ad15ca271c5/jbc-20-400-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85fc/5744001/ec9b6756a40b/jbc-20-400-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85fc/5744001/3ad15ca271c5/jbc-20-400-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85fc/5744001/ec9b6756a40b/jbc-20-400-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85fc/5744001/3ad15ca271c5/jbc-20-400-g002.jpg

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本文引用的文献

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Society of Surgical Oncology-American Society for Radiation Oncology-American Society of Clinical Oncology Consensus Guideline on Margins for Breast-Conserving Surgery With Whole-Breast Irradiation in Ductal Carcinoma In Situ.外科肿瘤学会-美国放射肿瘤学会-美国临床肿瘤学会关于导管原位癌保乳手术联合全乳照射切缘的共识指南。
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Diagnostic Accuracy of Intraoperative Techniques for Margin Assessment in Breast Cancer Surgery: A Meta-analysis.乳腺癌手术中切缘评估的术中技术诊断准确性:一项荟萃分析。
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Assessment of Practice Patterns Following Publication of the SSO-ASTRO Consensus Guideline on Margins for Breast-Conserving Therapy in Stage I and II Invasive Breast Cancer.
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Ann Surg Oncol. 2015 Oct;22(10):3250-6. doi: 10.1245/s10434-015-4666-1. Epub 2015 Jul 23.
4
Survey of American and Canadian general surgeons' perceptions of margin status and practice patterns for breast conserving surgery.美国和加拿大普通外科医生对保乳手术切缘状态及实践模式的认知调查。
Breast J. 2014 Sep-Oct;20(5):481-8. doi: 10.1111/tbj.12299. Epub 2014 Jun 26.
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Impact of analysis of frozen-section margin on reoperation rates in women undergoing lumpectomy for breast cancer: evaluation of the National Surgical Quality Improvement Program data.乳腺癌保乳术后因冰冻切缘分析而行再次手术的影响:国家外科质量改进计划数据评估。
Surgery. 2014 Jul;156(1):190-7. doi: 10.1016/j.surg.2014.03.025. Epub 2014 Mar 18.
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