Schauwecker D S
Department of Radiology, Indiana University School of Medicine, Indianapolis 46202.
Radiology. 1989 Apr;171(1):141-6. doi: 10.1148/radiology.171.1.2928518.
In a retrospective review, 485 patients with suspected osteomyelitis were studied. Of these, 453 patients were studied with both bone and indium-111 leukocyte scanning (173 sequentially and 280 simultaneously). The ability to determine that the infection was in bone rather than in adjacent soft tissue was greater with simultaneous bone scan and In-111 leukocyte studies than with sequential studies. The locations of suspected osteomyelitis were divided into central (containing active bone marrow), peripheral (hands and feet), and middle (between central and peripheral). Specificity remained high (about 90%) regardless of the location. Overall sensitivity was significantly lower in the central location than in the peripheral or middle location. Determination of whether the In-111 leukocyte activity was in bone or adjacent soft tissue was also more difficult when the infection was in the central location. For acute osteomyelitis, sensitivity was high regardless of the location. For chronic osteomyelitis, sensitivity was lower in the central location.
在一项回顾性研究中，对485例疑似骨髓炎患者进行了研究。其中，453例患者同时接受了骨扫描和铟-111白细胞扫描（173例为序贯扫描，280例为同步扫描）。与序贯研究相比，同步骨扫描和铟-111白细胞研究在确定感染位于骨而非相邻软组织方面的能力更强。疑似骨髓炎的部位分为中央型（含活跃骨髓）、周围型（手和脚）和中间型（中央与周围之间）。无论部位如何，特异性均保持在较高水平（约90%）。总体敏感性在中央型部位显著低于周围型或中间型部位。当感染位于中央型部位时，确定铟-111白细胞活性是在骨内还是在相邻软组织内也更加困难。对于急性骨髓炎，无论部位如何，敏感性都很高。对于慢性骨髓炎，中央型部位的敏感性较低。
