Togashi K, Nishimura K, Sagoh T, Minami S, Noma S, Fujisawa I, Nakano Y, Konishi J, Ozasa H, Konishi I
Department of Radiology, Kyoto University School of Medicine, Japan.
Radiology. 1989 Apr;171(1):245-51. doi: 10.1148/radiology.171.1.2928532.
Demonstration and staging of carcinoma of the cervix with magnetic resonance (MR) imaging was evaluated prospectively in 67 patients with histologically proven lesions. Findings were correlated with surgical/pathologic results obtained within 2 weeks. MR imaging had an accuracy of 95% in demonstrating invasive disease (stage IB or higher). It was capable of depicting the location and extent of tumor invasion of cervical stroma and helped detect tumor beneath relatively normal epithelium or within the endocervical canal that had not been detected by means of colposcopic biopsy. The overall accuracy of MR imaging in staging carcinoma of the cervix was 76%, and in demonstrating parametrial status, the overall accuracy was 89%. In 39 patients with proven invasive disease, the accuracy in demonstrating parametrial status was 82%. In 13 of these 39 patients the low-signal-intensity stromal ring of the cervix on MR images was completely preserved and there were no false-positive results. MR imaging is a highly promising method for directly demonstrating and staging carcinoma of the cervix and seems to be capable of providing answers to crucial questions regarding mode of therapy.
对67例经组织学证实患有宫颈病变的患者进行了前瞻性评估，以探讨磁共振（MR）成像在宫颈癌的显示及分期中的应用。将检查结果与在2周内获得的手术/病理结果进行了对比。MR成像在显示浸润性疾病（IB期或更高分期）方面的准确率为95%。它能够描绘肿瘤对宫颈基质的浸润位置和范围，并有助于检测在相对正常上皮下方或宫颈管内未被阴道镜活检检测到的肿瘤。MR成像在宫颈癌分期中的总体准确率为76%，在显示宫旁组织状态方面，总体准确率为89%。在39例经证实患有浸润性疾病的患者中，显示宫旁组织状态的准确率为82%。在这39例患者中的13例中，MR图像上宫颈的低信号强度基质环完全保留，且无假阳性结果。MR成像是一种极具前景的直接显示宫颈癌并进行分期的方法，似乎能够为有关治疗方式的关键问题提供答案。
