Kunduz Enver, Seri N Kursat Rahmi, Seker Mesut
Department of General Surgery, Faculty of Medicine, Bezmialem University, Istanbul 34093, Turkey.
Bosphorus Clinical Sciences Academy, Istanbul 34357, Turkey.
Mol Clin Oncol. 2017 Dec;7(6):1122-1124. doi: 10.3892/mco.2017.1467. Epub 2017 Oct 23.
Cholangiocarcinomas are the second most common primary liver malignancies. The lymphatics are the common route of metastatic spread for cholangiocarcinomas. The most frequent sites of metastasis are the liver, abdominal lymph nodes, peritoneum and lungs. Cutaneous metastasis of cholangiocarcinoma is rare, and most commonly occurs following percutaneous biliary drainage. Brain or skull metastases from this tumor are uncommon. However, these rare metastatic lesions may occasionally be the first disease manifestation, although scalp recurrence following curative treatment is uncommon. We herein present the cases of two patients with cholangiocarcinoma, who were evaluated as resectable based on the criteria for cholangiocarcinoma resectability, and developed scalp recurrence following curative hepatectomy. Therefore, although scalp recurrence is a rare occurrence following curative treatment for cholangiocarcinoma, metastases should be included in the differential diagnosis.
胆管癌是第二常见的原发性肝脏恶性肿瘤。淋巴管是胆管癌转移扩散的常见途径。最常见的转移部位是肝脏、腹部淋巴结、腹膜和肺部。胆管癌的皮肤转移很少见，最常发生在经皮胆道引流之后。该肿瘤的脑或颅骨转移并不常见。然而，这些罕见的转移病灶偶尔可能是首发的疾病表现，尽管根治性治疗后头皮复发并不常见。我们在此报告两例胆管癌患者的病例，他们根据胆管癌可切除性标准被评估为可切除，并且在根治性肝切除术后出现了头皮复发。因此，尽管胆管癌根治性治疗后头皮复发很少见，但在鉴别诊断时应考虑转移的可能性。
