Kumar K V S H, Patnaik S K
Department of Endocrinology, Army Hospital (Research and Referral), New Delhi, India.
Department of Pediatrics, Army Hospital (Research and Referral), New Delhi, India.
Indian J Endocrinol Metab. 2017 Nov-Dec;21(6):809-811. doi: 10.4103/2230-8210.219335.
The comprehensive epidemiology of endocrine disorders is lacking from our country. Most of the available data pertain to the prevalence of diabetes and thyroid disorders only. We studied the incidence of endocrine disorders in a cohort of service personnel followed for a long duration.
The data for this descriptive epidemiologic study were derived from the electronic medical records of the male service personnel enrolled between 1990 and 2015. They were recruited between the ages of 17 and 20 years in good health, and their morbidity data were derived from the medical records. We calculated the incidence rates as per person-years (py) using appropriate statistical methods.
Our analysis includes 51,217 participants (median: age 33 years, range: 17-54) with a mean follow-up of 12.5 years. Yearly evaluation of the data gave a cumulative follow-up duration of 613,925 py. The incidence of diabetes, obesity, and dyslipidemia was 0.41, 0.23, and 0.12 per 1000 py, respectively. The incidence of thyroid, parathyroid, pituitary, adrenal, and metabolic bone disorders was 3.9, 8.6, 1.6, 0.81, and 0.97 per 100,000 py, respectively.
Our cohort had lower incidence rates of endocrine disorders when compared with the Western population. Long-term epidemiological studies are essential to identify the demographic trends of the endocrine disorders in India.
我国缺乏内分泌疾病的综合流行病学数据。现有的大多数数据仅涉及糖尿病和甲状腺疾病的患病率。我们对一组长期随访的服务人员的内分泌疾病发病率进行了研究。
这项描述性流行病学研究的数据来自1990年至2015年登记的男性服务人员的电子病历。他们在17至20岁时健康状况良好时被招募,其发病数据来自病历。我们使用适当的统计方法计算了每人年(py)的发病率。
我们的分析包括51217名参与者(中位数:年龄33岁,范围:17 - 54岁),平均随访12.5年。对数据的年度评估得出累积随访时长为613925人年。糖尿病、肥胖症和血脂异常的发病率分别为每1000人年0.41、0.23和0.12。甲状腺、甲状旁腺、垂体、肾上腺和代谢性骨疾病的发病率分别为每100000人年3.9、8.6、1.6、0.81和0.97。
与西方人群相比,我们队列中的内分泌疾病发病率较低。长期的流行病学研究对于确定印度内分泌疾病的人口趋势至关重要。