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微聚焦超声联合稀释羟基磷灰石钙用于改善颈部和胸部皮肤松弛及皱纹外观。

Microfocused ultrasound in combination with diluted calcium hydroxylapatite for improving skin laxity and the appearance of lines in the neck and décolletage.

作者信息

Casabona Gabriela, Nogueira Teixeira Diana

机构信息

Clínica Vida, São Paulo, Brazil.

PharmaWrite Medical Communications, Würzburg, Germany.

出版信息

J Cosmet Dermatol. 2018 Feb;17(1):66-72. doi: 10.1111/jocd.12475. Epub 2017 Dec 29.

DOI:10.1111/jocd.12475
PMID:29285863
Abstract

BACKGROUND

Skin laxity and wrinkling on the neck and décolletage reveal age as reliably as the face.

OBJECTIVE

To evaluate the combined use of microfocused ultrasound with visualization (MFU-V; Ultherapy ) and diluted calcium hydroxylapatite (CaHA; Radiesse ) for treating the neck and décolletage.

METHODS

Subjects with moderate-to-severe lines on the neck and/or décolletage were retrospectively enrolled. MFU-V was applied using 7 and 10 MHz transducers followed by subdermal injection of CaHA diluted 1:1 with lidocaine solution. Photographs at baseline and 90 days were assessed by two independent, blinded evaluators using three scales: Merz Aesthetics décolleté wrinkles, Fabi-Bolton chest wrinkle, and Allergan transverse neck lines scales.

RESULTS

A total of 47 subjects were treated as follows: 29 (neck only), five (décolletage only), and 13 (both areas). Mean neckline score improved from 2.6 (moderate-to-severe lines) at baseline to 1.3 (mild lines) 90 days after treatment (P < .001). Mean décolletage scores improved from 2.6 and 3.3 (moderate-to-severe wrinkles) on the Merz Aesthetics and Fabi-Bolton scales, respectively, to 1.1 and 1.8 (mild wrinkles), respectively, after treatment (both P < .001). Both procedures were well tolerated with high subject satisfaction.

CONCLUSIONS

Combining MFU-V with 1:1 diluted CaHA is effective for improving the appearance of neck and décolletage lines and wrinkles.

摘要

背景

颈部和胸部皮肤的松弛与皱纹和面部一样能可靠地显示年龄。

目的

评估微聚焦超声可视化技术(MFU-V;超声刀)与稀释的羟基磷灰石钙(CaHA;瑞蓝唯瑅)联合用于治疗颈部和胸部的效果。

方法

回顾性纳入颈部和/或胸部有中度至重度皱纹的受试者。使用7兆赫和10兆赫的换能器进行MFU-V治疗,随后皮下注射用利多卡因溶液1:1稀释的CaHA。由两名独立的、不知情的评估人员使用三种量表对基线和90天时的照片进行评估:默茨美学胸部皱纹量表、法比-博尔顿胸部皱纹量表和艾尔建横向颈部皱纹量表。

结果

共有47名受试者接受了如下治疗:29名(仅颈部)、5名(仅胸部)和13名(两个部位)。颈部皱纹平均评分从基线时的2.6分(中度至重度皱纹)改善至治疗后90天的1.3分(轻度皱纹)(P <.001)。胸部皱纹在默茨美学量表和法比-博尔顿量表上的平均评分分别从2.6分和3.3分(中度至重度皱纹)改善至治疗后的1.1分和1.8分(轻度皱纹)(均P <.001)。两种治疗方法耐受性良好,受试者满意度高。

结论

MFU-V与1:1稀释的CaHA联合使用可有效改善颈部和胸部皱纹的外观。

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