Naselli Aldo, Accame Laura, Buffa Piero, Loy Anna, Bandettini Roberto, Garaventa Alberto, Della Casa Alberighi Ornella, Castagnola Elio
Infectious Diseases Unit, Istituto Giannina Gaslini - Ospedale Pediatrico IRCCS, Genova, Italy.
Clinical Pharmacology Unit, Scientific Direction, Istituto Giannina Gaslini - Ospedale Pediatrico IRCCS, Genova, Italy.
Infez Med. 2017 Dec 1;25(4):358-361.
The use of sugar for treating wounds which are difficult to heal and positive to resistant pathogens has already been documented. The authors describe the successful treatment by direct instillation of granular sugar in the antibiotic-resistant infected surgical site wound of a child with sarcoma. Sugar instillation in the extended spectrum beta-lactamase (ESBL)-producing Enterobacter cloacae positive wound, in addition to systemic treatment with meropenem and levofloxacin, allowed culture negativization in six days and complete wound healing in 30 days. These results make the use of sugar an attractive option for wounds which are difficult to treat, even in an immunocompromised child.
糖用于治疗难以愈合且对耐药病原体呈阳性反应的伤口这一用途已有文献记载。作者描述了通过直接向一名患有肉瘤的儿童的抗生素耐药性感染手术部位伤口滴注颗粒状糖而取得成功治疗的案例。除了用美罗培南和左氧氟沙星进行全身治疗外，在产超广谱β-内酰胺酶（ESBL）的阴沟肠杆菌阳性伤口中滴注糖，使得伤口在六天内培养结果转为阴性，并在30天内完全愈合。这些结果表明，即使对于免疫功能低下的儿童，糖也是治疗难治性伤口的一个有吸引力的选择。
