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结晶性乳腺囊肿的细胞学诊断——1例罕见病例报告

Cytological diagnosis of crystallizing galactocele - report of an unusual case.

作者信息

Jaseem Hassan Mohammad, Sharma Monika, Khetrapal Shaan, Khan Sabina, Jetley Sujata

出版信息

Breast Dis. 2018;37(3):159-161. doi: 10.3233/BD-170295.

DOI:10.3233/BD-170295
PMID:29286912
Abstract

Crystallizing galactocele is a very rare entity which yields a viscous, chalky material on Fine Needle Aspiration Cytology (FNAC). FNAC is used both for diagnosis as well as treatment of this condition. We present here a case of 26 years old lactating female who presented with swelling in the right breast for 8 months. The swelling was firm, discrete, non-tender and mobile involving the upper inner quadrant of right breast. A diagnosis of benign breast disease, possibly fibroadenoma was made clinically. FNAC of the lesion yielded thick, milky and chalky material. Cytological smears showed numerous semitransparent crystals of varying size and shapes with angulated borders in a background of granular and amorphous debris along with frothy appearing micelles. These crystals show positive birefringence. Based on clinical history of lactation and typical cytological findings, a diagnosis of crystallizing galactocele was made. We report this case because of rarity of this condition and to the best of our knowledge, till date only five cases of crystallizing galactocele has been reported in medical literature.

摘要

结晶性积乳囊肿是一种非常罕见的疾病,在细针穿刺抽吸细胞学检查(FNAC)中可产生一种粘性的、白垩样物质。FNAC可用于该疾病的诊断和治疗。我们在此报告一例26岁的哺乳期女性,她右乳肿胀8个月。肿块质地硬、边界清晰、无压痛且可活动,累及右乳的上内象限。临床诊断为良性乳腺疾病,可能为纤维腺瘤。对该病变进行FNAC检查,抽出了浓稠、呈乳状和白垩样的物质。细胞学涂片显示,在颗粒状和无定形碎片背景中,有许多大小和形状各异、边界呈角状的半透明晶体,以及呈泡沫状的微胶粒。这些晶体显示正双折射。根据哺乳期的临床病史和典型的细胞学表现,诊断为结晶性积乳囊肿。我们报告这例病例是因为这种疾病罕见,据我们所知,迄今为止医学文献中仅报道过5例结晶性积乳囊肿。

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引用本文的文献

1
Crystallising galactocele of the breast: a rare cytological diagnosis.乳腺胶样囊肿结晶:一种罕见的细胞学诊断。
BMJ Case Rep. 2021 May 25;14(5):e242888. doi: 10.1136/bcr-2021-242888.
2
FNAC Diagnosis of Crystallizing Galactocele- An Unusual Presentation.细针穿刺抽吸活检术诊断结晶性乳腺囊肿——一种不寻常的表现
J Cytol. 2020 Jul-Sep;37(3):149-150. doi: 10.4103/JOC.JOC_18_20. Epub 2020 Jun 30.