Arora Suman, Gupta Priyanka, Arya Virender Kumar, Bhatia Nidhi
Post Graduate Institute of Medical Education and Research (PGIMER, Department of Anaesthesia and Intensive Care, Chandigarh, Índia.
All India Institute of Medical Sciences (AIIMS), New Delhi, Índia.
Braz J Anesthesiol. 2018 Mar-Apr;68(2):128-134. doi: 10.1016/j.bjan.2017.09.006. Epub 2017 Dec 27.
Efficacy of preoxygenation depends upon inspired oxygen concentration, its flow rate, breathing system configuration and patient characteristics. We hypothesized that in actual clinical scenario, where breathing circuit is not primed with 100% oxygen, patients may need more time to achieve EtO ≥ 90%, and this duration may be different among various breathing systems. We thus studied the efficacy of preoxygenation using unprimed Mapleson A, Bain's and Circle system with tidal volume breathing at oxygen flow rates of 5 L.min and 10 L.min.
Patients were randomly allocated into one of the six groups, wherein they were preoxygenated using either Mapleson A, Bain's or Circle system at O flow rate of either 5 L.min or 10 L.min. The primary outcome measure of our study was the time taken to achieve EtO ≥ 90% at 5 and 10 L.min flow rates.
At oxygen flow rate of 5 L.min, time to reach EtO ≥ 90% was significantly longer with Bain's system (3.7 ± 0.67 min) than Mapleson A and Circle system (2.9 ± 0.6, 3.3 ± 0.97 min, respectively). However at oxygen flow rate of 10 L.min this time was significantly shorter and comparable among all the three breathing systems (2.33 ± 0.38 min with Mapleson, 2.59 ± 0.50 min with Bain's and 2.60 ± 0.47 min with Circle system).
With spontaneous normal tidal volume breathing at oxygen flow rate of 5 L.min, Mapleson A can optimally preoxygenate patients within 3 min while Bain's and Circle system require more time. However at O flow rate of 10 L.min all the three breathing systems are capable of optimally preoxygenating the patients in less than 3 min.
预充氧的效果取决于吸入氧浓度、其流速、呼吸回路配置和患者特征。我们推测,在实际临床场景中,呼吸回路未用100%氧气预充时,患者可能需要更多时间才能使呼气末氧浓度(EtO)≥90%,并且这个持续时间在不同的呼吸回路系统中可能有所不同。因此,我们研究了在未预充的Mapleson A系统、贝恩系统和环路系统中,以5 L/min和10 L/min的氧流速进行潮气量呼吸时的预充氧效果。
患者被随机分配到六组中的一组,在该组中,他们使用Mapleson A系统、贝恩系统或环路系统,以5 L/min或10 L/min的氧流速进行预充氧。我们研究的主要结局指标是在5 L/min和10 L/min的流速下达到EtO≥90%所需的时间。
在氧流速为5 L/min时,使用贝恩系统达到EtO≥90%的时间(3.7±0.67分钟)明显长于Mapleson A系统和环路系统(分别为2.9±0.6分钟和3.3±0.97分钟)。然而,在氧流速为10 L/min时,这个时间明显缩短,并且在所有三种呼吸回路系统中相当(Mapleson系统为2.33±0.38分钟,贝恩系统为2.59±0.50分钟,环路系统为2.60±0.47分钟)。
在氧流速为5 L/min进行自主正常潮气量呼吸时,Mapleson A系统可在3分钟内为患者进行最佳预充氧,而贝恩系统和环路系统则需要更多时间。然而,在氧流速为10 L/min时,所有三种呼吸回路系统都能够在不到3分钟的时间内为患者进行最佳预充氧。