Karunaratne Kushan, Taube David, Khalil Nofal, Perry Richard, Malhotra Paresh A
Department of Neurology, Imperial College Healthcare NHS Trust, London, UK.
Department of Renal and Transplantation Medicine, West London Renal and Transplant Centre, Imperial College Kidney and Transplant Institute, London, UK.
Pract Neurol. 2018 Apr;18(2):115-125. doi: 10.1136/practneurol-2017-001657. Epub 2017 Dec 28.
Neurological complications from renal replacement therapy contribute significantly to morbidity and mortality in patients with renal failure. Such complications can affect either the central or peripheral nervous systems. Most neurological disturbances associated with the uraemic state do not respond fully to renal replacement therapy. There are also complications specifically associated with dialysis and transplantation. A multidisciplinary approach, involving both nephrologists and neurologists, is critical for the diagnosis and effective management of these disorders.
肾脏替代治疗引起的神经并发症是导致肾衰竭患者发病和死亡的重要因素。此类并发症可影响中枢神经系统或周围神经系统。大多数与尿毒症状态相关的神经功能障碍对肾脏替代治疗反应并不完全。还有一些并发症与透析和移植特别相关。采用多学科方法,包括肾病学家和神经学家,对于这些疾病的诊断和有效管理至关重要。