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[临床实践中获得性痣细胞痣的管理]

[Management of acquired nevus-cell nevi in clinical practice].

作者信息

Sigg C

出版信息

Ther Umsch. 1989 Feb;46(2):133-7.

PMID:2928982
Abstract

The alarming increase in the incidence of malignant melanoma and the lack of an effective therapy in metastasizing forms focussed the interest on the early curable stages and the precursors (or tumor markers) of malignant melanoma such as dysplastic nevi. Familial variants of dysplastic nevus syndrome (DNS) are associated with increased risk for malignant melanoma; the significance of sporadic dysplastic nevi, however, remains to be elucidated. Until more is known about which clinically dysplastic lesions, if any, can be left with complete safety, it is reasonable to remove all nevi which one cannot say are with certainty benign.

摘要

恶性黑色素瘤发病率的惊人增长以及转移性黑色素瘤缺乏有效治疗方法,使得人们的关注点集中在恶性黑色素瘤的早期可治愈阶段及其前驱病变(或肿瘤标志物),如发育异常痣。发育异常痣综合征(DNS)的家族性变体与恶性黑色素瘤风险增加相关;然而,散发性发育异常痣的意义仍有待阐明。在更多地了解哪些临床发育异常病变(如果有的话)可以完全安全地留存之前,切除所有不能确定为良性的痣是合理的。

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