Cohen R, Raymond J, Gendrel D
Université Paris Est, IMRB-GRC GEMINI, 94000 Créteil, France; Unité Court Séjour, Petits Nourrissons, Service de Néonatologie, Centre Hospitalier Intercommunal de Créteil, France; Association Clinique et Thérapeutique Infantile du Val de Marne (ACTIV), Saint-Maur des Fossés, France; Groupe de Pathologie Infectieuse Pédiatrique de la Société Française de Pédiatrie (GPIP), Saint-Maur des Fossés, France.
Groupe de Pathologie Infectieuse Pédiatrique de la Société Française de Pédiatrie (GPIP), Saint-Maur des Fossés, France; Université Paris Descartes. Hôpital Cochin, Paris France.
Arch Pediatr. 2017 Dec;24(12S):S26-S29. doi: 10.1016/S0929-693X(17)30515-8.
Acute gastroenteritis (AGE) are usually caused by viruses, especially Rotavirus and Norovirus. Among the bacterial causes, very few warrant antibiotic treatment, mainly Shigella, Vibrio cholerae, Campylobacter (only for severe cases, particularly in the initial phase) and severe cases of Salmonella infection. The antimicrobial treatments proposed in this guide follow the latest guidelines of the European Society of Pediatric Infectious Diseases and the European Society of Pediatric Gastroenterology and Nutrition. Azithromycin is the preferred antibiotic for infections due to Shigella and Campylobacter. Ceftriaxone and ciprofloxacin are recommended for salmonellosis when antibiotic treatment is indicated. In most cases, empirical treatment without bacteriological documentation should be avoided.
急性胃肠炎(AGE)通常由病毒引起,尤其是轮状病毒和诺如病毒。在细菌病因中,很少需要抗生素治疗,主要是志贺氏菌、霍乱弧菌、弯曲杆菌(仅用于重症病例,特别是在初始阶段)以及严重的沙门氏菌感染病例。本指南中提出的抗菌治疗遵循欧洲儿科传染病学会和欧洲儿科胃肠病学与营养学会的最新指南。阿奇霉素是治疗志贺氏菌和弯曲杆菌感染的首选抗生素。当需要抗生素治疗时,推荐头孢曲松和环丙沙星用于治疗沙门氏菌病。在大多数情况下,应避免在没有细菌学证据的情况下进行经验性治疗。