Gueudry J, Muraine M
Service d'ophtalmologie, hôpital Charles-Nicolle, CHU de Rouen, 1, rue de Germont, 76031 Rouen cedex, France.
Service d'ophtalmologie, hôpital Charles-Nicolle, CHU de Rouen, 1, rue de Germont, 76031 Rouen cedex, France.
J Fr Ophtalmol. 2018 Jan;41(1):e11-e21. doi: 10.1016/j.jfo.2017.11.003. Epub 2017 Dec 29.
Anterior Uveitis is the most common form of uveitis. There are several known and many possible etiologies for anterior uveitis. After examining the posterior segment and ruling out masquerade syndromes, the main step of etiologic diagnosis is clinical characterization. It is essential to establish the presence or absence of unilateral versus bilateral and granulomatous features. Subsequently, a directed work-up may be obtained which then helps to confirm diagnostic hypotheses based on the detailed history and clinical examination. The priority is to rule out an infection. Treatments are adapted according to etiology and disease severity. Finally, biologics have greatly changed the management and prevention of some forms of anterior uveitis, in particular uveitis associated with HLA-B27 and juvenile idiopathic arthritis-associated anterior uveitis.
前葡萄膜炎是葡萄膜炎最常见的形式。前葡萄膜炎有几种已知病因，还有许多可能的病因。在检查眼后段并排除伪装综合征后，病因诊断的主要步骤是进行临床特征描述。确定是否存在单侧与双侧以及肉芽肿性特征至关重要。随后，可进行针对性的检查，这有助于根据详细病史和临床检查来证实诊断假设。首要任务是排除感染。治疗方法根据病因和疾病严重程度进行调整。最后，生物制剂极大地改变了某些形式的前葡萄膜炎的管理和预防，特别是与HLA - B27相关的葡萄膜炎以及青少年特发性关节炎相关的前葡萄膜炎。
