Lupovitch A, Chen R, Mishra S
Department of Pathology, Holy Cross Hospital, Detroit, MI 48234.
Acta Cytol. 1989 Mar-Apr;33(2):259-62.
The fine needle aspiration (FNA) cytologic features are described in a case of inflammatory pseudotumor of the liver (xanthogranuloma), a disease generally regarded as of unknown etiology. The initial FNA findings were those of an acute exudative process, with atypical biliary duct epithelium and hepatocytes. These were interpreted as verifying the radiologic impression of a malignancy. Histologic study of subsequently resected nodules revealed the true nature of the case. As the lesion evolved, granulomatous inflammation supervened, characterized by numerous foamy histiocytes and lesser populations of plasma cells and lymphocytes. Numerous gram-positive cocci were readily demonstrated, suggesting that the lesion was an unusual tissue response to an intrahepatic bacterial infection. The lesion eventually resolved with prolonged antibiotic therapy.
本文描述了一例肝脏炎性假瘤（黄色肉芽肿）的细针穿刺抽吸（FNA）细胞学特征，该疾病病因通常不明。最初的FNA检查结果显示为急性渗出性病变，伴有非典型胆管上皮细胞和肝细胞。这些结果被解释为证实了影像学上恶性肿瘤的印象。随后对切除结节的组织学研究揭示了该病例的真实性质。随着病变的发展，出现了肉芽肿性炎症，其特征为大量泡沫状组织细胞以及少量浆细胞和淋巴细胞。很容易发现大量革兰氏阳性球菌，提示该病变是对肝内细菌感染的一种异常组织反应。经长期抗生素治疗后，病变最终消退。
