Nakajima T, Sugano I, Matsuzaki O, Nagao K, Kondo Y, Miyazaki M, Konno A, Shimura T
Department of Surgical Pathology, Teikyo University School of Medicine, Ichihara Hospital, Japan.
Arch Pathol Lab Med. 1993 Feb;117(2):157-9.
We report two surgical cases of inflammatory conditions of the liver that, on imaging studies, closely resembled a neoplasm. Under the diagnoses of hepatic malignant neoplasms, both patients underwent hepatic resections. Histologically, one case was found to be a hepatic xanthogranuloma (an inflammatory pseudotumor) that consisted of foamy histiocytes, plasma cells, lymphocytes, and fibroblasts, while the other case was found to be an epithelioid cell granuloma with a central area of coagulative necrosis. Although their exact pathogenesis remained obscure, cholangitis in the former case and tuberculosis in the latter were assumed to be possible causal factors. Special attention should be paid to these unusual conditions in terms of the differential diagnosis of hepatic mass lesions.
我们报告了两例肝脏炎症性疾病的外科病例，这些病例在影像学检查中与肿瘤极为相似。在被诊断为肝脏恶性肿瘤的情况下，两名患者均接受了肝脏切除术。组织学检查发现，其中一例为肝黄色肉芽肿（一种炎性假瘤），由泡沫状组织细胞、浆细胞、淋巴细胞和成纤维细胞组成，而另一例为上皮样细胞肉芽肿，中央有凝固性坏死区。尽管其确切发病机制尚不清楚，但推测前者的胆管炎和后者的结核病可能是致病因素。在肝脏肿块病变的鉴别诊断方面，应特别关注这些不寻常的情况。
