Johansson Emma
Karolinska Institutet - Enheten för dermatologi och venereologi, Institutionen för medicin Solna Stockholm, Sweden Karolinska Institutet - Enheten för dermatologi och venereologi, Institutionen för medicin Solna Stockholm, Sweden.
Lakartidningen. 2017 Nov 21;114:EUEC.
Atopic eczema common at all ages Eczema (atopic dermatitis) is an inflammatory skin disorder with dry skin and recurrent episodes of inflammation and itch. Onset is most common the first two years of life, but also occurs among older children, adolescents and adults. The prevalence of eczema has increased in Sweden and other industrialized countries the last decades; 15-30% of children and 2-10% of adults are affected. Approximately half of children with eczema early in life are in remission in adolescence. However, many of these will relapse later in life, often as hand eczema. Children with eczema are at increased risk to develop IgE sensitization to common food- and airborne allergens, food allergy, asthma and rhinitis. In addition, recent studies have reported that having eczema is associated with non-allergic disorders such as ADHD, depression and anxiety, epilepsy, overweight and obesity, cardiovascular disease, and different kinds of malignancies. There are also studies that have not found an association between eczema and the above mentioned non-allergic comorbidities. Thus, the association between eczema and non-allergic comorbidities are still largely unknown.
特应性湿疹在各年龄段均常见 湿疹(特应性皮炎)是一种炎症性皮肤病,伴有皮肤干燥以及炎症和瘙痒的反复发作。发病最常见于生命的头两年,但也发生于大龄儿童、青少年和成年人中。在过去几十年里,瑞典和其他工业化国家湿疹的患病率有所上升;15% - 30%的儿童和2% - 10%的成年人受到影响。大约一半在幼年患有湿疹的儿童在青春期病情缓解。然而,其中许多人在以后的生活中会复发,通常表现为手部湿疹。患有湿疹的儿童发生对常见食物和空气传播过敏原的IgE致敏、食物过敏、哮喘和鼻炎的风险增加。此外,最近的研究报告称,患有湿疹与注意力缺陷多动障碍、抑郁和焦虑、癫痫、超重和肥胖、心血管疾病以及各种恶性肿瘤等非过敏性疾病有关。也有研究未发现湿疹与上述非过敏性合并症之间存在关联。因此,湿疹与非过敏性合并症之间的关联在很大程度上仍然未知。