Berg O, Carenfelt C, Halldén G, Hed J
Department of Otolaryngology, Karolinska Hospital, Stockholm, Sweden.
Acta Otolaryngol. 1989 Jan-Feb;107(1-2):130-5. doi: 10.3109/00016488909127489.
Granulocytes in sinus pus and in peripheral blood in 28 patients with maxillary sinus empyema were compared to blood granulocytes obtained from healthy blood donors. A flow cytofluorometric assay technique was used to establish the C3b-mediated phagocytosis and the CR1-receptor expression. The results indicate that a subpopulation of viable granulocytes in situ was activated with an increased ability to ingest particles. From 11 of 28 patients, an increased CR1-expression was also demonstrated in the blood samples, reflecting a priming of the circulating granulocytes before extravasation.
对28例上颌窦积脓患者鼻窦脓液和外周血中的粒细胞与健康献血者的血液粒细胞进行了比较。采用流式细胞荧光分析技术测定C3b介导的吞噬作用和CR1受体表达。结果表明，原位存活粒细胞亚群被激活，吞噬颗粒的能力增强。28例患者中有11例血液样本中CR1表达也增加，这反映了循环粒细胞在渗出前的预激发状态。
