Niv Yaron
Department of Gastroenterology, Rabin Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Eur J Gastroenterol Hepatol. 2018 Mar;30(3):247-251. doi: 10.1097/MEG.0000000000001062.
Adenoma detection rate (ADR) is defined as the number of colonoscopies with at least one adenoma, expressed as the ratio of the total number of colonoscopies performed. Recently, an application of a conversion factor to estimate the ADR from the polyp detection rate (PDR) was described.
In this meta-analysis, we examined the correlation between ADR and PDR in the published studies and assessed the relative ratio of these ratios for a better and more accurate estimation.
English Medical literature searches were performed for 'PDR' AND 'ADR'. A meta-analysis was carried out for papers that fulfilled the inclusion criteria using comprehensive meta-analysis software.
Twenty-five studies and 42 sets of data, including 31 623 patients, from nine countries published till 31 August 2017, were found. Funnel plot did not indicate a significant publication bias. relative ratio for ADR calculated from PDR was 0.688, 95% confidence intervals: 0.680-0.695, P value of less than 0.0001 in the meta-analysis fixed model. Heterogeneity (the proportion of inconsistency in individual studies) between studies was significant, with Q=492.753, d.f. (Q) 41, P<0.0001, and I 91.679.
We found the ratio of 0.688 can be used to calculate ADR from PDR for the individual endoscopist or for a group of endoscopists before receiving the formal results from the pathology department.
腺瘤检出率（ADR）定义为至少有一个腺瘤的结肠镜检查数量，以所进行的结肠镜检查总数的比例表示。最近，描述了一种应用转换因子从息肉检出率（PDR）估计ADR的方法。
在这项荟萃分析中，我们研究了已发表研究中ADR与PDR之间的相关性，并评估了这些比率的相对比值，以进行更好、更准确的估计。
对英文医学文献进行“PDR”和“ADR”的检索。使用综合荟萃分析软件对符合纳入标准的论文进行荟萃分析。
共检索到截至2017年8月31日发表的来自9个国家的25项研究和42组数据，包括31623例患者。漏斗图未显示明显的发表偏倚。在荟萃分析固定模型中，由PDR计算得出的ADR相对比值为0.688，95%置信区间：0.680 - 0.695，P值小于0.0001。研究间的异质性（个体研究中不一致的比例）显著，Q = 492.753，自由度（Q）41，P < 0.0001，I² = 91.679。
我们发现0.688这个比值可用于在病理科给出正式结果之前，由个体内镜医师或一组内镜医师根据PDR计算ADR。
