Meyer Moritz F, Schoch Anja, Jansen Stefanie, Hüttenbrink Karl-Bernd, Beutner Dirk
Department of Otorhinolaryngology, Head and Neck Surgery, University of Cologne.
Department of Otorhinolaryngology, Head and Neck Surgery, University Medical Center Göttingen, Göttingen, Germany.
Otol Neurotol. 2018 Mar;39(3):e203-e208. doi: 10.1097/MAO.0000000000001667.
Previously, it was demonstrated how the Eustachian tube (ET) opening function can be influenced by middle ear pressure and movement of the tympanic membrane via neural control. Mechanoreceptors on the tympanic membrane may be part of the afferent arc and could influence the middle ear pressure by activating the musculus veli palatini as part of a reflex.
In a hypo and hyperbaric pressure chamber, 17 participants (34 ears) were twice exposed to a standardized pressure profile of pressure decrease and increase. The ET function reflecting parameters-ET opening pressure (ETOP), ET opening duration (ETOD), and ET opening frequency (ETOF)-were determined before and after local anesthesia of the right tympanic membrane.
After pressure exposure by pressure increase (active induced equalization) and pressure decrease (passive equalization) there was no significant difference between the mean value of ETOP, ETOD, and ETOF before and after local anesthesia of the right tympanic membrane on the right (anesthetized) or left side (not anesthetized).
These results may lead to the hypothesis that tympanic membrane mechanoreceptors may play a minor role in regulating the ET function in humans.
此前，已证明咽鼓管（ET）开放功能如何通过神经控制受中耳压力和鼓膜运动的影响。鼓膜上的机械感受器可能是传入弧的一部分，并可作为反射的一部分通过激活腭帆肌来影响中耳压力。
在一个低压和高压压力舱中，17名参与者（34只耳朵）两次暴露于标准化的压力降低和升高的压力曲线下。在右侧鼓膜局部麻醉前后，测定反映ET功能的参数——ET开放压力（ETOP）、ET开放持续时间（ETOD）和ET开放频率（ETOF）。
在压力升高（主动诱导平衡）和压力降低（被动平衡）的压力暴露后，右侧（麻醉）或左侧（未麻醉）鼓膜局部麻醉前后的ETOP、ETOD和ETOF平均值之间没有显著差异。
这些结果可能导致这样的假设，即鼓膜机械感受器在调节人类ET功能中可能起次要作用。
