Hoffman Mark, Norcross Marc, Johnson Sam
College of Public Health and Human Sciences, Oregon State University, Corvallis, Oregon, USA.
Neuroreport. 2018 Mar 7;29(4):314-316. doi: 10.1097/WNR.0000000000000961.
To compare the maximum Hoffmann reflex (H-reflex) and the maximum M-wave (H : M) ratio of the H-reflex in men and women when all participants showed similar saliva levels of estradiol and progesterone. This is a cohort design study involving healthy men and women with a mean age of 22.4±3.4 years. The H : M ratio of the H-reflex was assessed in women and men at a point in time when naturally occurring levels of estradiol and progesterone were similar. The female participants had a significantly higher H : M ratio compared with the male participants, whereas no differences in the saliva levels of progesterone and estradiol were detected. This is the first study to report differences between women and men in the H : M ratio of the H-reflex. An additional novel aspect of this study is that the assessments were performed when the levels of neuroactive sex hormones (estradiol and progesterone) were similar in all participants.
当所有参与者的雌二醇和孕酮唾液水平相似时，比较男性和女性的最大霍夫曼反射（H反射）以及H反射的最大M波（H∶M）比值。这是一项队列设计研究，涉及平均年龄为22.4±3.4岁的健康男性和女性。在雌二醇和孕酮的自然水平相似的时间点，对女性和男性的H反射H∶M比值进行评估。与男性参与者相比，女性参与者的H∶M比值显著更高，而在孕酮和雌二醇的唾液水平上未检测到差异。这是第一项报告男性和女性在H反射H∶M比值上存在差异的研究。本研究的另一个新颖之处在于，评估是在所有参与者的神经活性性激素（雌二醇和孕酮）水平相似时进行的。
