Hoffman Julien I
Department of Pediatrics, University of California, San Francisco, CA, USA. Email:
Cardiovasc J Afr. 2018;29(4):252-255. doi: 10.5830/CVJA-2017-053. Epub 2017 Dec 11.
Critical coarctation of the aorta in neonates is a common cause of shock and death. It may be the most difficult of all forms of critical congenital heart disease to diagnose because the obstruction from the coarctation does not appear until several days after birth (and after discharge from the hospital), and because there are no characteristic murmurs. Some of these patients may be detected by neonatal screening by pulse oximetry, but only a minority is so diagnosed. Older patients are usually asymptomatic but, although clinical diagnosis is easy, they are frequently undiagnosed.
新生儿主动脉严重缩窄是休克和死亡的常见原因。它可能是所有类型的严重先天性心脏病中最难诊断的，因为缩窄造成的梗阻在出生几天后（以及出院后）才会出现，而且没有特征性杂音。这些患者中的一些可能通过脉搏血氧测定法进行新生儿筛查时被发现，但只有少数能得到这样的诊断。年龄较大的患者通常没有症状，虽然临床诊断容易，但他们常常未被诊断出来。
