Salavastru C, Tiplica G S, Branisteanu D E, Fritz K
Abteilung für Pädiatrische Dermatologie, Colentina-Krankenhaus, 19-21 Stefan cel Mare Av., Bukarest, Rumänien.
Medizinische und Pharmazeutische Universität Carol Davila, Bukarest, Rumänien.
Hautarzt. 2018 Jan;69(1):27-34. doi: 10.1007/s00105-017-4099-9.
Light-based acne treatments may represent a new emerging treatment for acne that does not increase the risk of bacterial resistance and they may be potentially effective with a favorable safety profile. Current data show that photodynamic therapy reduces inflammatory lesions and significantly improves acne. However, there is no consensus on the optimal implementation in the treatment of acne. In addition to topically applied photodynamic therapy, intense pulsed light, pulsed dye lasers, potassium-titanyl-phosphate lasers, infrared diode lasers, broad-spectrum continuous-wave light sources (red light, blue-red light) have been introduced as alternative treatments. Since well-designed studies to evaluate their efficacy versus traditional medical therapies are lacking and standardized regimens have not been agreed upon, procedures including laser, intense pulsed light, and photodynamic therapy should currently not be considered first-line treatment for inflammatory acne.
基于光的痤疮治疗方法可能代表了一种新出现的痤疮治疗手段，不会增加细菌耐药性风险，而且可能具有良好的安全性和潜在疗效。目前的数据表明，光动力疗法可减少炎性皮损并显著改善痤疮。然而，在痤疮治疗的最佳实施方式上尚未达成共识。除了局部应用光动力疗法外，强脉冲光、脉冲染料激光、磷酸钛氧钾激光、红外二极管激光、广谱连续波光光源（红光、红蓝光）已被作为替代治疗方法引入。由于缺乏评估其与传统药物疗法疗效对比的精心设计研究，且尚未就标准化方案达成一致，目前激光、强脉冲光和光动力疗法等治疗手段不应被视为炎性痤疮的一线治疗方法。
