Clinic for Birds, Small Mammals, Reptiles and Ornamental Fish, Center for Clinical Veterinary Medicine, Ludwig-Maximilians-Universitaet Muenchen, Sonnenstr. 18, 85764, Oberschleißheim, Germany.
Arch Virol. 2018 Apr;163(4):895-909. doi: 10.1007/s00705-017-3688-3. Epub 2018 Jan 2.
Polyomavirus infections were detected in 40 companion bird individuals belonging to a broad species range of estrildid and fringillid finches and originating from 21 different bird aviaries. Based on partial virus protein 1 (VP1) sequences, the viruses were identified as Serinus canaria polyomavirus 1 and Pyrrhula pyrrhula polyomavirus 1. Serinus canaria polyomavirus 1 was found in 18 birds belonging to one estrildid and four fringillid species. Pyrrhula pyrrhula polyomavirus 1 was detected in 22 birds of six estrildid and three fringillid species. There was a large overlap in host range. Increased mortality was frequently found in the affected bird aviaries while clinical signs were diverse. Co-infections with other viruses, bacteria or fungal pathogens were common and might have influenced the clinical signs. Sequence analyses, including partial VP1 sequences of the 40 virus strains, and full genome sequences of selected strains revealed a high genetic heterogeneity among virus subgroups of Serinus canaria polyomavirus 1 and Pyrrhula pyrrhula polyomavirus 1, indicating the existence of two virus variants for both virus species. For Pyrrhula pyrrhula polyomavirus 1, two genotypes were found that associated with the family of the finches, Estrildidae or Fringillidae.
在来自 21 个不同鸟舍的 40 只长尾鹦鹉科和雀形目科的各种雀鸟中，检测到了多瘤病毒感染。基于病毒蛋白 1（VP1）的部分序列，这些病毒被鉴定为栗耳草雀多瘤病毒 1 和黄腹山雀多瘤病毒 1。栗耳草雀多瘤病毒 1 存在于 18 只属于一个长尾鹦鹉科和四个雀形目科的鸟类中。黄腹山雀多瘤病毒 1 存在于 6 个长尾鹦鹉科和 3 个雀形目科的 22 只鸟类中。宿主范围有很大的重叠。受影响的鸟舍中经常发现死亡率增加，而临床症状则多种多样。与其他病毒、细菌或真菌病原体的合并感染很常见，可能影响了临床症状。序列分析，包括 40 株病毒的部分 VP1 序列和选定株的全长基因组序列，揭示了栗耳草雀多瘤病毒 1 和黄腹山雀多瘤病毒 1 的病毒亚群之间存在高度遗传异质性，表明这两种病毒都存在两种病毒变体。对于黄腹山雀多瘤病毒 1，发现了两种与雀形目科的 Estrildidae 或 Fringillidae 相关的基因型。
