Sciorsci R L, Piccinno M, Rizzo A
Department of Emergency and Organ Transplantation, Section of Veterinary Medicine and Animal Production, University of Bari Aldo Moro, S.P. per Casamassima km. 3, 70010, Valenzano, BA, Italy.
Department of Emergency and Organ Transplantation, Section of Veterinary Medicine and Animal Production, University of Bari Aldo Moro, S.P. per Casamassima km. 3, 70010, Valenzano, BA, Italy.
Theriogenology. 2018 Mar 1;108:348-353. doi: 10.1016/j.theriogenology.2017.12.033. Epub 2017 Dec 27.
The objective of this in vitro study was to evaluate and compare the effects of scopolamine butylbromide (Spasmolax) on xylazine-sensitized bovine pregnant uterine strips, at different stages of pregnancy. The procedures were carried out in isolated organ bath. Uterine motility, expressed with amplitude, frequency of contractions as well as the area under the curve, was recorded in different stages of pregnancy and data were collected at 5-min intervals starting 5 min before treatment until 10 min after treatment (5-min after xylazine administration and 5-min after scopolamine butylbromide addition). The results suggest that scopolamine butylbromide might decrease the tonic effect induced by xylazine on bovine pregnant uteri from 0-30 days to 240-270 days.
本体外研究的目的是评估和比较丁溴东莨菪碱（解痉灵）对不同妊娠阶段的赛拉嗪致敏牛妊娠子宫条的影响。实验步骤在离体器官浴槽中进行。记录不同妊娠阶段子宫的运动情况，以收缩幅度、频率以及曲线下面积表示，并在治疗前5分钟开始，每隔5分钟收集数据，直至治疗后10分钟（赛拉嗪给药后5分钟和丁溴东莨菪碱添加后5分钟）。结果表明，丁溴东莨菪碱可能会降低赛拉嗪对妊娠0 - 30天至240 - 270天的牛妊娠子宫的强直作用。
