Pogliani E M, Cortellaro M, Foa P, Iurlo A, Polli E E
Institute of Medical Sciences, Milan, Italy.
Am J Hematol. 1989 Apr;30(4):257-8. doi: 10.1002/ajh.2830300413.
We report on a 62 year-old woman who developed a severe aplastic anemia requiring frequent packed red cell and platelet transfusions. Since conventional pharmacological therapy was ineffective, treatment with Cyclosporin A was started, resulting in a significant increase of leukocyte, platelet, and red cell counts. However, 5 months after the beginning of Cyclosporin A treatment, despite a past medical history not significant for clinical tuberculosis, the patient developed tubercular pericarditis. This report underlines the need for a careful follow-up of Cyclosporin A-treated patients aimed at a prompt diagnosis of possible infectious complications.
我们报告了一名62岁女性，她患上了严重再生障碍性贫血，需要频繁输注浓缩红细胞和血小板。由于传统药物治疗无效，遂开始使用环孢素A进行治疗，结果白细胞、血小板和红细胞计数显著增加。然而，在开始环孢素A治疗5个月后，尽管患者既往无临床结核病病史，但却患上了结核性心包炎。本报告强调了对接受环孢素A治疗的患者进行仔细随访的必要性，以便及时诊断可能的感染并发症。
