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基因内扩增：B 细胞前体急性淋巴细胞白血病中的一个新亚组？

Intragenic amplification of : a novel subgroup in B-cell precursor acute lymphoblastic leukemia?

作者信息

Schwab Claire, Nebral Karin, Chilton Lucy, Leschi Cristina, Waanders Esmé, Boer Judith M, Žaliová Markéta, Sutton Rosemary, Öfverholm Ingegerd Ivanov, Ohki Kentaro, Yamashita Yuka, Groeneveld-Krentz Stefanie, Froňková Eva, Bakkus Marleen, Tchinda Joelle, Barbosa Thayana da Conceição, Fazio Grazia, Mlynarski Wojciech, Pastorczak Agata, Cazzaniga Giovanni, Pombo-de-Oliveira Maria S, Trka Jan, Kirschner-Schwabe Renate, Imamura Toshihiko, Barbany Gisela, Stanulla Martin, Attarbaschi Andishe, Panzer-Grümayer Renate, Kuiper Roland P, den Boer Monique L, Cavé Hélène, Moorman Anthony V, Harrison Christine J, Strehl Sabine

机构信息

Leukaemia Research Cytogenetics Group, Wolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, United Kingdom.

Children's Cancer Research Institute, St Anna Kinderkrebsforschung, Vienna, Austria.

出版信息

Blood Adv. 2017 Aug 14;1(19):1473-1477. doi: 10.1182/bloodadvances.2017006734. eCollection 2017 Aug 22.

DOI:10.1182/bloodadvances.2017006734
PMID:29296789
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5728462/
Abstract

Intragenic amplification defines a novel, relapse-prone subtype of B-cell precursor acute lymphoblastic leukemia with a poor outcome.

摘要

基因内扩增定义了一种新的、易复发的B细胞前体急性淋巴细胞白血病亚型，其预后较差。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a96/5728462/b21774bd3b2f/advances006734absf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a96/5728462/b21774bd3b2f/advances006734absf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a96/5728462/b21774bd3b2f/advances006734absf1.jpg

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