一个携带新型胚系突变的家族中急性髓系白血病的索引病例。
Index case of acute myeloid leukemia in a family harboring a novel germ line mutation.
作者信息
Ram Jodi, Flamm Gabrielle, Balys Marlene, Sivagnanalingam Umayal, Rothberg Paul G, Iqbal Anwar, Myers Jason R, Corbett Anthony, Ashton John M, Mendler Jason H
机构信息
James P. Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY.
出版信息
Blood Adv. 2017 Mar 14;1(8):500-503. doi: 10.1182/bloodadvances.2017004424.
Abstract
The persistence of a mutation at the time of complete remission warrants germ line analysis.Not all patients harboring germ line mutations have a family history of AML.
摘要
完全缓解时突变的持续存在需要进行生殖系分析。并非所有携带生殖系突变的患者都有急性髓系白血病家族史。
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