眼中的一滴泪——对全身有影响吗？
A Single Drop in the Eye - Effects on the Whole Body?
作者信息
Vaajanen Anu, Vapaatalo Heikki
机构信息
Department of Ophthalmology, Tampere University Hospital, P.O. Box 2000, 33521 Tampere, Finland.
SILK, Department of Ophthalmology, School of Medicine, University of Tampere, 33014, Tampere, Finland.
出版信息
Open Ophthalmol J. 2017 Oct 31;11:305-314. doi: 10.2174/1874364101711010305. eCollection 2017.
Abstract
INTRODUCTION
Although the local adverse effects of ophthalmic drugs, including allergic reactions, are well recognized, less is known about the systemic side- effects of eye drops, especially during pregnancy, breast-feeding and early childhood. Ophthalmologists should also be aware of unusual, in some cases even life-threatening, effects of commonly used eye drops.
CONCLUSION
This brief review outlines the routes of systemic absorption and the kinetics of active components present in eye drops, and identifies the clinically relevant systemic adverse effects.
摘要
引言
尽管眼科药物的局部不良反应，包括过敏反应，已广为人知，但对于眼药水的全身副作用，尤其是在孕期、哺乳期和儿童早期的副作用，人们了解较少。眼科医生还应了解常用眼药水的异常副作用，在某些情况下甚至是危及生命的副作用。
结论
本简要综述概述了眼药水活性成分的全身吸收途径和动力学，并确定了临床上相关的全身不良反应。
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