生殖细胞的亚细胞特化和细胞器行为。
Subcellular Specialization and Organelle Behavior in Germ Cells.
机构信息
Life Sciences Institute, Department of Cell and Developmental Biology, Howard Hughes Medical Institute, University of Michigan, Ann Arbor, Michigan 48109
出版信息
Genetics. 2018 Jan;208(1):19-51. doi: 10.1534/genetics.117.300184.
Abstract
Gametes, eggs and sperm, are the highly specialized cell types on which the development of new life solely depends. Although all cells share essential organelles, such as the ER (endoplasmic reticulum), Golgi, mitochondria, and centrosomes, germ cells display unique regulation and behavior of organelles during gametogenesis. These germ cell-specific functions of organelles serve critical roles in successful gamete production. In this chapter, I will review the behaviors and roles of organelles during germ cell differentiation.
摘要
配子、卵子和精子是高度特化的细胞类型，新生命的发育完全依赖于它们。尽管所有细胞都共享必需的细胞器，如内质网（ER）、高尔基体、线粒体和中心体，但生殖细胞在配子发生过程中表现出细胞器的独特调节和行为。这些细胞器在生殖细胞中的特定功能在成功产生配子中起着关键作用。在本章中，我将回顾细胞器在生殖细胞分化过程中的行为和作用。
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