Calza G, Panizzon G, Rovida S, Aigueperse J
Department of Cardiovascular Surgery, Istituto Giannina Gaslini, Genova, Italy.
Ann Thorac Surg. 1989 Mar;47(3):428-35. doi: 10.1016/0003-4975(89)90387-1.
The postoperative results in 150 patients who had repair of tetralogy of Fallot (mean follow-up, 10.2 +/- 2.6 years) were defined as good in 71.3%, fair in 20.7%, and unsatisfactory in 8.0% on the basis of clinical criteria. Ninety-six percent of the patients are socially active, 92.0% have a good exercise tolerance, and 79.3% participate in sports. Data from 78 postoperative hemodynamic studies show mild right ventricular dysfunction in almost all patients examined. Peak systolic right ventricular/left ventricular pressure ratio decreased in the postoperative period in 65.4% of patients, remained unchanged in 3.8%, and increased in 30.8%. Minimal residual anomalies can modify the prognosis substantially. Of our patients, 53.3% of those with a shunt (p less than 0.05), 37.5% of those with stenosis (not significant), and 53.8% of those with pulmonary incompetences (p = not significant) have fair or unsatisfactory results. The associated defects are particularly unfavorable. Rhythm and conduction disturbances have resulted in fair or unsatisfactory results in 65.1% of patients. Such a disturbance occurring soon after bypass must be considered an incremental risk factor: 52.9% of patients seen with rhythm and conduction disturbances show the same disturbances later (p less than 0.001).
对150例法洛四联症修复术后患者(平均随访时间为10.2±2.6年)的术后结果,根据临床标准判定为良好的占71.3%,中等的占20.7%,不满意的占8.0%。96%的患者社交活动正常,92.0%的患者运动耐量良好,79.3%的患者参加体育活动。78例术后血流动力学研究数据显示,几乎所有接受检查的患者均存在轻度右心室功能障碍。65.4%的患者术后收缩期右心室/左心室压力峰值比下降,3.8%的患者保持不变,30.8%的患者升高。微小的残余异常可显著改变预后。在我们的患者中,有分流的患者中有53.3%(p<0.05)、有狭窄的患者中有37.5%(无显著差异)、有肺动脉瓣关闭不全的患者中有53.8%(p=无显著差异)的结果为中等或不满意。合并的缺陷尤其不利。心律失常和传导障碍导致65.1%的患者结果为中等或不满意。体外循环后不久出现的这种障碍必须被视为一个增加的危险因素:出现心律失常和传导障碍的患者中有52.9%随后仍有相同的障碍(p<0.001)。