Chen D, Moller J H
Am Heart J. 1987 Mar;113(3):767-72. doi: 10.1016/0002-8703(87)90718-6.
Long-term results and postoperative hemodynamic findings were reviewed in 144 cases of tetralogy of Fallot. A correlation was found between the late clinical status of patients and the postoperative hemodynamic findings. The mortality in our series of patients followed for 10 years was 6.25%. Each of the deaths occurred in the group with unsatisfactory postoperative hemodynamic findings. An ideal late clinical result can be anticipated in most patients with excellent or satisfactory postoperative hemodynamic findings. The greater the deviation from normal hemodynamic findings, the worse the prognosis. From the excellent group to the unsatisfactory group, the incidence of late ideal result decreased from 95% to 61.1%, while the incidence of poor result increased from 0% to 27.8%. Among various factors in patients in the unsatisfactory hemodynamic group, right ventricular outflow tract obstruction seems to have the worst late result. A large right ventricular-pulmonary artery pressure gradient was noted in three of four who died suddenly. The late result of patients with a small shunt (pulmonary blood flow/systemic blood flow less than 2) seems acceptable; the decision to reoperate in these patients should be made very cautiously.
对144例法洛四联症患者的长期结果和术后血流动力学结果进行了回顾。发现患者的晚期临床状况与术后血流动力学结果之间存在相关性。在我们随访10年的患者系列中,死亡率为6.25%。每例死亡均发生在术后血流动力学结果不理想的组中。大多数术后血流动力学结果优秀或满意的患者可预期获得理想的晚期临床结果。与正常血流动力学结果的偏差越大,预后越差。从优秀组到不满意组,晚期理想结果的发生率从95%降至61.1%,而差结果的发生率从0%升至27.8%。在血流动力学不满意组的患者的各种因素中,右心室流出道梗阻似乎晚期结果最差。在4例突然死亡的患者中,有3例存在较大的右心室-肺动脉压力梯度。小分流(肺血流量/体循环血流量小于2)患者的晚期结果似乎可以接受;对这些患者进行再次手术的决定应非常谨慎地做出。