Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of the Ministry of Education, College of Chemistry & Materials Science, Northwest University , Xi'an 710069, China.
State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University , Lanzhou 730000, China.
J Am Chem Soc. 2018 Jan 17;140(2):586-589. doi: 10.1021/jacs.7b11591. Epub 2018 Jan 8.
The nickel-catalyzed decarbonylation of unstrained diaryl ketones has been developed. The reaction is catalyzed by a combination of Ni(cod) and an electron-rich N-heterocyclic carbene ligand. High functional group tolerance and excellent yields (up to 98%) are observed. This strategy provides an alternative and versatile approach to construct biaryls using an inexpensive nickel catalyst.
镍催化的未应变二芳基酮脱羰基化反应已经被开发出来。该反应是由 Ni(cod) 和富电子的 N-杂环卡宾配体共同催化的。该反应具有高官能团容忍度和优异的产率（高达 98%）。该策略提供了一种使用廉价镍催化剂构建联芳基的替代和通用方法。
